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- 抗原 See all HLA-E 抗体
- HLA-E (HLA Class I Histocompatibility Antigen, alpha Chain E (HLA-E))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This HLA-E antibody is un-conjugated
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应用范围
- Flow Cytometry (FACS), Immunoprecipitation (IP)
- 原理
- Mouse monoclonal antibody raised against recombinant HLA-E.
- 特异性
- This antibody recognized native surface-expressed HLA-E, but not denaturated heavy chain of HLA-E. HLA-E belongs to the MHC Class I molecules (MHC Class Ib, nonclassical) and it is expressed on many types of the human cells. The published results revealed that antibody is remarkably specific to HLA-E, only with weak cross-reactivity with following classical MHC Class I molecules (MHC Class Ia) : HLA-A24, -B7, -B27, -B51, -B54, -C7.
- 交叉反应
- 人
- 免疫原
- Recombinant protein corresponding to human HLA-E.
- 克隆位点
- MEM-E-08
- 亚型
- IgG1
- Top Product
- Discover our top product HLA-E Primary Antibody
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- 应用备注
- The optimal working dilution should be determined by the end user.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- In PBS, pH 7.4 (0.09 % sodium azide)
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
- 储存方法
- Store at 4°C. Do not freeze.
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The CD85J/leukocyte inhibitory receptor-1 distinguishes between conformed and beta 2-microglobulin-free HLA-G molecules." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 175, Issue 8, pp. 4866-74, (2005) (PubMed).
: "HLA-E surface expression is independent of the availability of HLA class I signal sequence-derived peptides in human tumor cell lines." in: Human immunology, Vol. 66, Issue 1, pp. 1-12, (2004) (PubMed).
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The CD85J/leukocyte inhibitory receptor-1 distinguishes between conformed and beta 2-microglobulin-free HLA-G molecules." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 175, Issue 8, pp. 4866-74, (2005) (PubMed).
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- 抗原
- HLA-E (HLA Class I Histocompatibility Antigen, alpha Chain E (HLA-E))
- 别名
- HLA class I alpha E / HLA-E (HLA-E 产品)
- 别名
- EA1.2 antibody, EA2.1 antibody, HLA-6.2 antibody, MHC antibody, QA1 antibody, major histocompatibility complex, class I, E antibody, HLA-E antibody, PATR-E antibody
- 基因ID
- 3133
- 途径
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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