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PMS2 抗体

PMS2 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1204 unconjugated
产品编号 ABIN533824
发货至: 中国
  • 抗原 See all PMS2 抗体
    PMS2 (PMS2 Postmeiotic Segregation Increased 2 (S. Cerevisiae) (PMS2))
    适用
    • 62
    • 11
    • 8
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 48
    • 13
    • 1
    小鼠
    克隆类型
    • 38
    • 24
    单克隆
    标记
    • 45
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This PMS2 antibody is un-conjugated
    应用范围
    • 40
    • 26
    • 15
    • 15
    • 9
    • 7
    • 6
    • 4
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA
    原理
    Mouse monoclonal antibody raised against partial recombinant PMS2.
    特异性
    This is an protein A purified antibody directed against PMS2-134 and reacts with full length version of PMS2 in human and hamster tissues. The epitope was putatively mapped to amino acids 58-81 of human PMS2.
    交叉反应
    Chimpanzee, 人, 小鼠, 大鼠
    产品特性
    Antibody Reactive Against Recombinant Protein.
    免疫原
    Recombinant protein corresponding to the first 133 amino acids of human PMS2.
    克隆位点
    1204
    亚型
    IgG1
    Top Product
    Discover our top product PMS2 Primary Antibody
  • 应用备注
    ELISA (1:5000-1:20000)
    Western Blot (1:500-1:2000)
    The optimal working dilution should be determined by the end user.
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    In 20 mM KH2PO4, 150 mM NaCl, pH 7.2 (0.01 % sodium azide)
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store at 4°C. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • de Jong, van Puijenbroek, Hendriks, Tops, Wijnen, Ausems, Meijers-Heijboer, Wagner, van Os, Bröcker-Vriends, Vasen, Morreau: "Microsatellite instability, immunohistochemistry, and additional PMS2 staining in suspected hereditary nonpolyposis colorectal cancer." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 10, Issue 3, pp. 972-80, (2004) (PubMed).

    Luo, Lin, Lin: "ATM-mediated stabilization of hMutL DNA mismatch repair proteins augments p53 activation during DNA damage." in: Molecular and cellular biology, Vol. 24, Issue 14, pp. 6430-44, (2004) (PubMed).

    Nakagawa, Lockman, Frankel, Hampel, Steenblock, Burgart, Thibodeau, de la Chapelle: "Mismatch repair gene PMS2: disease-causing germline mutations are frequent in patients whose tumors stain negative for PMS2 protein, but paralogous genes obscure mutation detection and interpretation." in: Cancer research, Vol. 64, Issue 14, pp. 4721-7, (2004) (PubMed).

    Lucci-Cordisco, Zito, Gensini, Genuardi: "Hereditary nonpolyposis colorectal cancer and related conditions." in: American journal of medical genetics. Part A, Vol. 122A, Issue 4, pp. 325-34, (2003) (PubMed).

  • 抗原
    PMS2 (PMS2 Postmeiotic Segregation Increased 2 (S. Cerevisiae) (PMS2))
    别名
    PMS2 (PMS2 产品)
    别名
    HNPCC4 antibody, PMS2CL antibody, PMSL2 antibody, AW555130 antibody, Pmsl2 antibody, PMS1 homolog 2, mismatch repair system component antibody, PMS1 homolog2, mismatch repair system component antibody, mismatch repair endonuclease PMS2 antibody, PMS2 antibody, Pms2 antibody, LOC463257 antibody, LOC107984056 antibody
    基因ID
    5395
    途径
    DNA Damage Repair, Production of Molecular Mediator of Immune Response
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