TAR DNA Binding Protein (TARDBP) 抗体

ABIN533778 产品详细信息
抗原
适用
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1
宿主
小鼠
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34
8
1
克隆类型 (克隆位点)
单克隆 ()
标记
非结合性
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6
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3
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应用范围
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), ELISA, Western Blotting (WB)
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选项
原理 Mouse monoclonal antibody raised against partial recombinant TARDBP.
免疫原 Recombinant protein corresponding to amino acids 1-260 of human TARDBP.
克隆位点 K1B8
亚型 IgG1, kappa
抗原
别名 TARDBP (TARDBP Antibody 摘要)
途径 Positive Regulation of Peptide Hormone Secretion
应用备注 The optimal working dilution should be determined by the end user.
限制 仅限研究用
状态 Liquid
缓冲液 In PBS, pH 7.4 (10 % glycerol, 0.02 % sodium azide).
储存条件 4 °C,-20 °C,-80 °C
储存方法 Store at 4°C for 1-2 weeks. For long term storage, store at -20°C to -80°C.
Aliquot to avoid repeated freezing and thawing.
厂商提供的图像
Image no. 1 for anti-TAR DNA Binding Protein (TARDBP) antibody (ABIN533778) Paraffin embedded sections of human colon cancer tissue were incubated with TARDBP mo...
Image no. 2 for anti-TAR DNA Binding Protein (TARDBP) antibody (ABIN533778) Cell lysates of HeLa (20 ug) were resolved by SDS-PAGE and probed with TARDBP monoclo...
有引用在: Zeineddine, Pundavela, Corcoran, Stewart, Do-Ha, Bax, Guillemin, Vine, Hatters, Ecroyd, Dobson, Turner, Ooi, Wilson, Cashman, Yerbury: "SOD1 protein aggregates stimulate macropinocytosis in neurons to facilitate their propagation." in: Molecular neurodegeneration, Vol. 10, pp. 57, 2015 (PubMed).

Kabashi, Valdmanis, Dion, Spiegelman, McConkey, Vande Velde, Bouchard, Lacomblez, Pochigaeva, Salachas, Pradat, Camu, Meininger, Dupre, Rouleau: "TARDBP mutations in individuals with sporadic and familial amyotrophic lateral sclerosis." in: Nature genetics, Vol. 40, Issue 5, pp. 572-4, 2008 (PubMed).

Rutherford, Zhang, Baker, Gass, Finch, Xu, Stewart, Kelley, Kuntz, Crook, Sreedharan, Vance, Sorenson, Lippa, Bigio, Geschwind, Knopman, Mitsumoto, Petersen, Cashman, Hutton, Shaw, Boylan, Boeve et al.: "Novel mutations in TARDBP (TDP-43) in patients with familial amyotrophic lateral sclerosis. ..." in: PLoS genetics, Vol. 4, Issue 9, pp. e1000193, 2008 (PubMed).