我们推荐在您的浏览器上开启Javascript，以获得最佳效果。

DNMT1 抗体 (AA 637-650)

Name: DNMT1 抗体 (AA 637-650)
SKU: ABIN531980
Availability: OutOfStock

DNMT1 适用: 人 WB, IP, IF, ChIP, ICC, FACS, IHC (p), IHC (fro), IHC (ff) 宿主: 小鼠 Monoclonal 60B1220-1 unconjugated

Western blot analysis with DNMT1 monoclonal antibody, clone 60B1220.

Immunofluorescent staining of HeLa cells with DNMT1 monoclonal antibody, clone 60B1220.

Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human hepatocellular carcinoma with DNMT1 monoclonal antibody, clone 60B1220.

IHC

Flow cytometric analysis of HeLa cells with DNMT1 monoclonal antibody, clone 60B1220.

FACS

4 images

(11 references)

产品编号 ABIN531980

发货至: 中国

Datasheet as PDF

抗原 See all DNMT1 抗体

DNMT1 (DNA (Cytosine-5)-Methyltransferase 1 (DNMT1))
抗原表位
26

22

16

12

12

10

9

8

7

7

7

5

4

4

3

2

2

2

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1
AA 637-650
适用
198

56

46

3

2

1

1

1

1

1

1
人
宿主
151

47

1

1
小鼠
Compatible Secondaries
克隆类型
139

61
单克隆
标记
81

16

13

11

9

9

6

6

6

6

6

6

3

3

3

3

3

2

2

2

2

2
This DNMT1 antibody is un-conjugated
应用范围
128

63

46

41

32

31

28

16

15

14

13

13

4

3

3

2

1

1

1

1

1
Western Blotting (WB), Immunoprecipitation (IP), Immunofluorescence (IF), Chromatin Immunoprecipitation (ChIP), Immunocytochemistry (ICC), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Free Floating) (IHC (ff))

原理

Mouse monoclonal antibody raised against synthetic peptide of DNMT1.

序列

EKDDREDKEN AFKR

交叉反应

人, 小鼠, 斑马鱼

免疫原

A synthetic peptide corresponding to amino acids 637-650 of human DNMT1.

克隆位点

60B1220-1

亚型

IgG1

Top Product

Discover our top product DNMT1 Primary Antibody
anti-DNA (Cytosine-5)-Methyltransferase 1 (DNMT1) (AA 1-270) antibody
DNMT1 适用: 人 WB, IP, IF 宿主: 兔 Polyclonal unconjugated

anti-DNA (Cytosine-5)-Methyltransferase 1 (DNMT1) antibody
DNMT1 适用: 人, 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-DNA (Cytosine-5)-Methyltransferase 1 (DNMT1) antibody
KO Validated DNMT1 适用: 人 WB, IHC, IP, IF, ChIP 宿主: 兔 Monoclonal unconjugated

anti-DNA (Cytosine-5)-Methyltransferase 1 (DNMT1) (AA 1448-1594) antibody
DNMT1 适用: 人, 猴 WB, IHC, ELISA 宿主: 小鼠 Monoclonal 7C11A2 unconjugated

anti-DNA (Cytosine-5)-Methyltransferase 1 (DNMT1) (AA 21-120) antibody
DNMT1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-DNA (Cytosine-5)-Methyltransferase 1 (DNMT1) (AA 1-270) antibody
DNMT1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-DNA (Cytosine-5)-Methyltransferase 1 (DNMT1) (AA 881-914) antibody
DNMT1 适用: 人, 小鼠 WB, IF, IHC (p) 宿主: 兔 Polyclonal RB51461 unconjugated

anti-DNA (Cytosine-5)-Methyltransferase 1 (DNMT1) antibody
DNMT1 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-DNA (Cytosine-5)-Methyltransferase 1 (DNMT1) (AA 637-650) antibody
DNMT1 适用: 人 WB, IHC, IP, ChIP 宿主: 小鼠 Monoclonal 60B1220-1 unconjugated

anti-DNA (Cytosine-5)-Methyltransferase 1 (DNMT1) (AA 1317-1616) antibody
DNMT1 适用: 人 WB, IHC, ELISA, ICC, FACS 宿主: 小鼠 Monoclonal 1D5G2 unconjugated

应用备注

ChIP (1:20-1:1000)
Flow Cytometry
Immunocytochemistry (1:10)
Immunofluorescence (1:10)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:50-1:500)
Immunohistochemistry (Free floating sections) (1:500)
Immunohistoche

限制

仅限研究用
状态

Liquid

缓冲液

In PBS (0.05 % sodium azide)

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
Du, Li, You, Wang, Wang, Cao, Hu, Liu: "DNA methylation in cystathionine-γ-lyase (CSE) gene promoter induced by ox-LDL in macrophages and in apoE knockout mice." in: Biochemical and biophysical research communications, Vol. 469, Issue 3, pp. 776-82, (2016) (PubMed).

Li, Li, Du, Wang, You, Wang, Xu, Cheng, Cao, Liu, Hu: "Homocysteine Triggers Inflammatory Responses in Macrophages through Inhibiting CSE-H2S Signaling via DNA Hypermethylation of CSE Promoter." in: International journal of molecular sciences, Vol. 16, Issue 6, pp. 12560-77, (2015) (PubMed).

Siouda, Frecha, Accardi, Yue, Cuenin, Gruffat, Manet, Herceg, Sylla, Tommasino: "Epstein-Barr virus down-regulates tumor suppressor DOK1 expression." in: PLoS pathogens, Vol. 10, Issue 5, pp. e1004125, (2014) (PubMed).

Saidj, Cros, Hernandez-Vargas, Guarino, Sylla, Tommasino, Accardi: "Oncoprotein E7 from beta human papillomavirus 38 induces formation of an inhibitory complex for a subset of p53-regulated promoters." in: Journal of virology, Vol. 87, Issue 22, pp. 12139-50, (2013) (PubMed).

Du, Zhou, Liu, Jiang, Wang, Hu, Qi, Zhong, Wang, Li: "Arsenic induces functional re-expression of estrogen receptor ? by demethylation of DNA in estrogen receptor-negative human breast cancer." in: PLoS ONE, Vol. 7, Issue 4, pp. e35957, (2012) (PubMed).

Cheng, Auersperg, Leung: "Inhibition of p53 represses E-cadherin expression by increasing DNA methyltransferase-1 and promoter methylation in serous borderline ovarian tumor cells." in: Oncogene, Vol. 30, Issue 37, pp. 3930-42, (2011) (PubMed).

Ji, Yang, Yu, Yuan, Hu, Zhang, Yang, Pang, Li, Lu, Fu, Chen, Lin, Chen, Zhuang: "Epigenetic silencing of O6-methylguanine DNA methyltransferase gene in NiS-transformed cells." in: Carcinogenesis, Vol. 29, Issue 6, pp. 1267-75, (2008) (PubMed).

Guastafierro, Cecchinelli, Zampieri, Reale, Riggio, Sthandier, Zupi, Calabrese, Caiafa: "CCCTC-binding factor activates PARP-1 affecting DNA methylation machinery." in: The Journal of biological chemistry, Vol. 283, Issue 32, pp. 21873-80, (2008) (PubMed).

Xia, Schneider-Stock, Diestel, Habold, Krueger, Roessner, Naumann, Lendeckel: "Helicobacter pylori regulates p21(WAF1) by histone H4 acetylation." in: Biochemical and biophysical research communications, Vol. 369, Issue 2, pp. 526-31, (2008) (PubMed).

Villa, Pasini, Gutierrez, Morey, Occhionorelli, Viré, Nomdedeu, Jenuwein, Pelicci, Minucci, Fuks, Helin, Di Croce: "Role of the polycomb repressive complex 2 in acute promyelocytic leukemia." in: Cancer cell, Vol. 11, Issue 6, pp. 513-25, (2007) (PubMed).

Mabaera, Greene, Richardson, Conine, Kozul, Lowrey: "Neither DNA hypomethylation nor changes in the kinetics of erythroid differentiation explain 5-azacytidine's ability to induce human fetal hemoglobin." in: Blood, Vol. 111, Issue 1, pp. 411-20, (2007) (PubMed).
抗原

DNMT1 (DNA (Cytosine-5)-Methyltransferase 1 (DNMT1))

别名

DNMT1 (DNMT1 产品)

别名

cb1075 antibody, cb983 antibody, dmnt1 antibody, fb05h01 antibody, mta antibody, wu:fb05h01 antibody, ADCADN antibody, AIM antibody, CXXC9 antibody, DNMT antibody, HSN1E antibody, MCMT antibody, DDM2 antibody, DECREASED DNA METHYLATION 2 antibody, DMT01 antibody, DMT1 antibody, DNA METHYLTRANSFERASE antibody, DNA METHYLTRANSFERASE 01 antibody, DNA METHYLTRANSFERASE 1 antibody, MET2 antibody, METHYLTRANSFERASE 2 antibody, METHYLTRANSFERASE I antibody, METI antibody, methyltransferase 1 antibody, Cxxc9 antibody, Dnmt antibody, Dnmt1o antibody, MTase antibody, Met-1 antibody, Met1 antibody, MommeD2 antibody, m.MmuI antibody, DNA methyltransferase 1 antibody, DNA (cytosine-5-)-methyltransferase 1 antibody, methyltransferase 1 antibody, DNA methyltransferase (cytosine-5) 1 antibody, DNMT1 antibody, dnmt1 antibody, Dnmt1 antibody, MET1 antibody

基因ID

1786

途径

SARS-CoV-2 Protein Interactome, The Global Phosphorylation Landscape of SARS-CoV-2 Infection