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MAP1LC3A 抗体 (AA 1-12)

MAP1LC3A 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN5065903
发货至: 中国
  • 抗原 See all MAP1LC3A 抗体
    MAP1LC3A (Microtubule-Associated Protein 1 Light Chain 3 alpha (MAP1LC3A))
    抗原表位
    • 23
    • 21
    • 19
    • 15
    • 13
    • 11
    • 11
    • 10
    • 10
    • 8
    • 8
    • 7
    • 7
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    • 5
    • 3
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    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-12
    适用
    • 211
    • 106
    • 87
    • 12
    • 9
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 173
    • 44
    • 2
    克隆类型
    • 165
    • 54
    多克隆
    标记
    • 108
    • 18
    • 15
    • 14
    • 14
    • 13
    • 3
    • 3
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    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    This MAP1LC3A antibody is un-conjugated
    应用范围
    • 197
    • 95
    • 73
    • 46
    • 32
    • 32
    • 29
    • 14
    • 14
    • 13
    • 11
    • 10
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    Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)
    特异性
    Most abundant in heart, brain, liver, skeletal muscle and testis but absent in thymus and peripheral blood leukocytes.,Detects ~14 kDa. Band at 50 kDa is LC3A complex.
    交叉反应
    人, 小鼠, 大鼠
    纯化方法
    Peptide Affinity Purified
    免疫原
    Synthetic peptide from the N-terminal of Human LC3A (aa. 1-12)
    亚型
    IgG
    Top Product
    Discover our top product MAP1LC3A Primary Antibody
  • 应用备注
    • WB (1:1000)
    • ICC/IF (1:100)
    • optimal dilutions for assays should be determined by the user.
    说明

    A 1:1000 dilution of ABIN5065903 was sufficient for detection of LC3A in 15 μg of Human HeLa Cell Lysates by ECL immunoblot analysis using goat anti-rabbit IgG:HRP as the secondary antibody.

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    PBS, 50 % glycerol, 0.09 % sodium azide, Storage buffer may change when conjugated
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    -20°C
  • 抗原
    MAP1LC3A (Microtubule-Associated Protein 1 Light Chain 3 alpha (MAP1LC3A))
    别名
    LC3A (MAP1LC3A 产品)
    别名
    ATG8E antibody, LC3 antibody, LC3A antibody, MAP1ALC3 antibody, MAP1BLC3 antibody, 1010001H21Rik antibody, 4922501H04Rik antibody, LC3a antibody, MGC69006 antibody, zgc:77094 antibody, MGC89867 antibody, MAP1LC3A antibody, map1lc3a antibody, microtubule associated protein 1 light chain 3 alpha antibody, microtubule-associated protein 1 light chain 3 alpha antibody, microtubule associated protein 1 light chain 3 alpha S homeolog antibody, MAP1LC3A antibody, Map1lc3a antibody, map1lc3a.S antibody, map1lc3a antibody
    背景
    Light chain 3 (LC3) is a microtubule-associated protein with an approximate molecular mass of 17 kDa, and can be found ubiquitously throughout mammalian tissue. LC3 plays a role in autophagy, once the autophagic process is initiated in a cell, LC3 is conjugated to phosphatidylethanolamine to form LC3-II. This molecule is recruited to the autophagosome at the time of fusion with lysosomes, and LC3-II in autolysosomal lumen is degraded. Therefore, monitoring LC3 is an important tool for detecting autophagy and autophagy-related processes. LC3A is one of three isoforms which exhibits abundant expression in the heart, brain, liver, skeletal muscle, and testis but is absent in thymus and peripheral blood leukocytes.
    基因ID
    84557
    NCBI登录号
    NP_115903
    UniProt
    Q9H492
    途径
    Autophagy
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