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CRADD 抗体 (C-Term)

CRADD 适用: 人 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN500563
发货至: 中国
  • 抗原 See all CRADD 抗体
    CRADD (CASP2 and RIPK1 Domain Containing Adaptor with Death Domain (CRADD))
    抗原表位
    • 16
    • 7
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    • 47
    • 5
    • 2
    宿主
    • 42
    • 5
    • 1
    • 1
    克隆类型
    • 41
    • 8
    多克隆
    标记
    • 29
    • 5
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CRADD antibody is un-conjugated
    应用范围
    • 38
    • 21
    • 9
    • 8
    • 8
    • 5
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    特异性
    This antibody detects RAIDD at C-term.
    交叉反应 (详细)
    Species reactivity (tested):Human
    纯化方法
    Peptide affinity chromatography
    免疫原
    RAIDD antibody was raised against a peptide corresponding to amino acids near the carboxy terminus of human RAIDD.
    亚型
    IgG
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    Discover our top product CRADD Primary Antibody
  • 应用备注
    ELISA. Western blot: 1: 500 - 1: 1000, a 22 kDa band should be detected. Immunohistochemistry on paraffin sections.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 缓冲液
    PBS containing 0.02 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
  • 抗原
    CRADD (CASP2 and RIPK1 Domain Containing Adaptor with Death Domain (CRADD))
    别名
    RAIDD (CRADD 产品)
    别名
    cradd antibody, MGC89035 antibody, zgc:101717 antibody, CRADD antibody, DKFZp468A2219 antibody, LOC100226369 antibody, raidd antibody, MGC78788 antibody, MRT34 antibody, RAIDD antibody, CASP2 and RIPK1 domain containing adaptor with death domain antibody, CASP2 and RIPK1 domain containing adaptor with death, gene 1 antibody, CASP2 and RIPK1 domain containing adaptor with death, gene 2 S homeolog antibody, CRADD antibody, cradd.1 antibody, cradd antibody, cradd.2.S antibody, Cradd antibody
    背景
    Apoptosis, or programmed cell death, occurs during normal cellular differentiation and development of multicellular organisms. Apoptosis is induced by certain cytokines including TNF and Fas ligand of the TNF family through their death domain (DD)-containing receptors, TNFR1 and Fas. The death signals are transduced by a group of DD-containing adapter molecules. A novel cell death adapter was recently identified by two independent groups and designated RAIDD (RIP-associated ICH-1/CED-3-homologous protein with DD) and CRADD (caspase and RIP adapter with DD)1,RAIDD contains a DD and a CARD (for caspase recruitment domain) which interact with RIP and caspase, respectively, to transduce death signals. RAIDD is constitutively expressed in many tissues and mediates apoptosis caused by Fas and TNFR-1.Synonyms: CRADD, Caspase and RIP adapter with death domain, Death domain-containing protein CRADD, RIP-associated protein with a death domain
    基因ID
    8738
    UniProt
    P78560
    途径
    Apoptosis, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity
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