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PHAP1 抗体 (C-Term)

ANP32A 适用: 人, 小鼠 WB, IF, EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN500483
发货至: 中国
  • 抗原 See all PHAP1 (ANP32A) 抗体
    PHAP1 (ANP32A) (Acidic (Leucine-Rich) Nuclear phosphoprotein 32 Family, Member A (ANP32A))
    抗原表位
    • 7
    • 6
    • 6
    • 6
    • 5
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    • 52
    • 21
    • 18
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    人, 小鼠
    宿主
    • 47
    • 7
    克隆类型
    • 48
    • 6
    多克隆
    标记
    • 34
    • 6
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PHAP1 antibody is un-conjugated
    应用范围
    • 44
    • 32
    • 27
    • 12
    • 7
    • 7
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
    特异性
    This antibody detetcs ANP32A at center.
    交叉反应 (详细)
    Species reactivity (tested):Human, mouse
    纯化方法
    Peptide affinity chromatography
    免疫原
    PHAP I antibody was raised with a synthetic peptide corresponding to amino acids close to carboxy terminus of human PHAP I. .Remarks: This sequence is identical between human and rat PHAP I.
    亚型
    IgG
    Top Product
    Discover our top product ANP32A Primary Antibody
  • 应用备注
    ELISA. Western blot: 2 to 4 μg/mL. Immunocytochemistry.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 缓冲液
    PBS containing 0.02 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
  • 抗原
    PHAP1 (ANP32A) (Acidic (Leucine-Rich) Nuclear phosphoprotein 32 Family, Member A (ANP32A))
    别名
    ANP32A (ANP32A 产品)
    别名
    C15orf1 antibody, HPPCn antibody, I1PP2A antibody, LANP antibody, MAPM antibody, PHAP1 antibody, PHAPI antibody, PP32 antibody, Anp32 antibody, W91701 antibody, pp32 antibody, Anp32a antibody, CG5784 antibody, CT18148 antibody, CT42180 antibody, Dmel\\CG5784 antibody, anon-EST:fe3A2 antibody, wu:fj36e08 antibody, zgc:55516 antibody, ANP32D antibody, acidic nuclear phosphoprotein 32 family member A antibody, acidic (leucine-rich) nuclear phosphoprotein 32 family, member A antibody, CG5784 gene product from transcript CG5784-RB antibody, acidic nuclear phosphoprotein 32 family member A L homeolog antibody, ANP32A antibody, Anp32a antibody, Mapmodulin antibody, anp32a antibody, anp32a.L antibody
    背景
    Apoptosis is related to many diseases and development. Caspase-9 plays a central role in cell death induced by a variety of apoptosis activators. Cytochrome c, after released from mitochondria, binds to Apaf-1, which forms an apoptosome that in turn binds to and activate procaspase-9. Activated caspase-9 cleaves and activates the effector caspases (caspase-3, -6 and -7), which are responsible for the proteolytic cleavage of many key proteins in apoptosis. The tumor suppressor putative HLA-DR-associated proteins (PHAPs) were recently identified as important regulators of mitochondrion apoptosis (1). PHAP appears to facilitate apoptosome-medicated caspase-9 activation and to stimulate the mitochondrial apoptotic pathway. PHAP was also shown to oppose both Ras- and Myc-medicated cell transformation.Synonyms: Acidic leucine-rich nuclear phosphoprotein 32 family member A, Acidic nuclear phosphoprotein pp32, C15orf1, LANP, Leucine-rich acidic nuclear protein, MAPM, Mapmodulin, PHAP1, Potent heat-stable protein phosphatase 2A inhibitor I1PP2A, Putative HLA-DR-associated protein I
    基因ID
    8125
    UniProt
    P39687
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