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NDUFAF2 抗体 (C-Term)

NDUFAF2 适用: 人 WB, IF, EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN500282
发货至: 中国
  • 抗原 See all NDUFAF2 抗体
    NDUFAF2 (NADH Dehydrogenase (Ubiquinone) 1 alpha Subcomplex, Assembly Factor 2 (NDUFAF2))
    抗原表位
    • 15
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    • 1
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    C-Term
    适用
    • 46
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    • 2
    • 1
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    宿主
    • 46
    克隆类型
    • 46
    多克隆
    标记
    • 13
    • 5
    • 4
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    • 2
    • 1
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    This NDUFAF2 antibody is un-conjugated
    应用范围
    • 42
    • 23
    • 16
    • 13
    • 13
    • 6
    • 4
    • 3
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
    交叉反应 (详细)
    Species reactivity (tested):Human
    纯化方法
    Peptide affinity chromatography
    免疫原
    Mimitin antibody was raised against a 14 amino acid peptide from near the carboxy terminus of human Mimitin.
    亚型
    IgG
    Top Product
    Discover our top product NDUFAF2 Primary Antibody
  • 应用备注
    ELISA. Western blot: 1 - 2 μg/mL. Immunocytochemistry.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    PBS containing 0.02 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    -20 °C
    储存方法
    Store the antibody (in aliquots) at -20 °C.
  • 抗原
    NDUFAF2 (NADH Dehydrogenase (Ubiquinone) 1 alpha Subcomplex, Assembly Factor 2 (NDUFAF2))
    别名
    Mimitin (NDUFAF2 产品)
    别名
    B17.2L antibody, MMTN antibody, NDUFA12L antibody, mimitin antibody, Ndufa12l antibody, RGD1560158 antibody, NDUFAF2 antibody, ndufa12l antibody, zgc:101036 antibody, 1810058I14Rik antibody, C86051 antibody, NADH:ubiquinone oxidoreductase complex assembly factor 2 antibody, NADH:ubiquinone oxidoreductase complex assembly factor 2 L homeolog antibody, NADH dehydrogenase (ubiquinone) complex I, assembly factor 2 antibody, NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, assembly factor 2 antibody, NDUFAF2 antibody, Ndufaf2 antibody, ndufaf2.L antibody, ndufaf2 antibody
    背景
    Mimitin, a small mitochondrial protein, whose transcription is directly stimulated by c-Myc, is highly expressed in 80 % of esophageal squamous cell carcinomas (ESCC). Suppression of Mimitin expression by RNA interference had no effect in cancerous cell lines such as human cervical carcinoma or hepatocarcinoma cell lines, but caused a decrease in cell proliferation in human glioblastoma, embryonic lung fibroblastic cells, and ESCC, suggesting Mimitin may play a special role in these types of cells. Mimitin expression is also regulated by MAPK kinases and IL-1, but not through the NF-kB-related pathway. It will interact with the microtubular protein MAP1S and can affect the activities of caspase-3 and -7 in cells stimulated to develop apoptosis. Other experiments suggest that Mimitin also acts as a molecular chaperone for the assembly of the mitochondrial complex I.Synonyms: B17.2-like, Myc-induced mitochondrial protein, NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 2, NDUFA12L, NDUFAF2
    基因ID
    91942
    NCBI登录号
    NP_777549
    UniProt
    Q8N183
    途径
    SARS-CoV-2 Protein Interactome
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