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C21ORF45 抗体 (Alexa Fluor 680)

MIS18A 适用: 人, 小鼠, 大鼠 WB, IF (p) 宿主: 兔 Polyclonal Alexa Fluor 680
产品编号 ABIN5002479
发货至: 中国
  • 抗原 See all C21ORF45 (MIS18A) 抗体
    C21ORF45 (MIS18A) (MIS18 Kinetochore Protein Homolog A (MIS18A))
    适用
    • 17
    • 16
    • 15
    • 2
    • 2
    • 2
    • 2
    • 1
    人, 小鼠, 大鼠
    宿主
    • 17
    克隆类型
    • 17
    多克隆
    标记
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This C21ORF45 antibody is conjugated to Alexa Fluor 680
    应用范围
    • 17
    • 12
    • 3
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    交叉反应
    人, 小鼠, 大鼠
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human FASP1/C21orf45
    亚型
    IgG
    Top Product
    Discover our top product MIS18A Primary Antibody
  • 应用备注
    IF(IHC-P) 1:50-200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    C21ORF45 (MIS18A) (MIS18 Kinetochore Protein Homolog A (MIS18A))
    别名
    FASP1 (MIS18A 产品)
    别名
    B28 antibody, C21orf45 antibody, C21orf46 antibody, FASP1 antibody, MIS18alpha antibody, hMis18alpha antibody, 2610039C10Rik antibody, 2810018N07Rik antibody, RGD1310778 antibody, MIS18 kinetochore protein A antibody, MIS18A antibody, Mis18a antibody
    背景

    Synonyms: B28, C21orf46, FASP1, hMis18alpha, MaFF interacting protein, MAFIP, MIS18A, Protein Mis18 alpha, MS18A_HUMAN.

    Background: Mapping to chromosome 21, the FASP1 gene (FAPP1-associated protein 1) encodes a 233 amino acid protein that is homologous to the fission yeast protein Mis18. In yeast, Mis18 is localized to the centrosome and forms a complex with Mis16 to maintain the deacetylated state of histones specifically in the central core of centromeres. FASP1, also known as Protein Mis18-alpha and C21orf45, is required for the recruitment of CENP-A to centrosomes and is thereby essential for normal chromosome segregation during mitosis. With expression in testis, FASP1 exists as a homodimer, a heterodimer with MIS18B or is present in a complex containing other Mis18 family members. FASP1 has been shown to bind to pp5644 in Hela cells, where overexpression of pp5644 leads to inhibited growth and colony formation.

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