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STAT4 抗体 (Internal Region)

STAT4 适用: 人, 犬, Pig WB, EIA 宿主: 山羊 Polyclonal unconjugated
产品编号 ABIN499124
发货至: 中国
  • 抗原 See all STAT4 抗体
    STAT4 (Signal Transducer and Activator of Transcription 4 (STAT4))
    抗原表位
    • 33
    • 11
    • 8
    • 7
    • 6
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 613-627, Internal Region
    适用
    • 88
    • 53
    • 35
    • 5
    • 5
    • 5
    • 5
    • 4
    • 2
    • 2
    • 2
    • 1
    人, 犬, Pig
    宿主
    • 96
    • 6
    • 2
    • 2
    山羊
    克隆类型
    • 87
    • 19
    多克隆
    标记
    • 54
    • 8
    • 7
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This STAT4 antibody is un-conjugated
    应用范围
    • 78
    • 48
    • 41
    • 24
    • 22
    • 16
    • 13
    • 13
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    序列
    C-DHSESGEVRF HSVEP
    特异性
    Recognizes STAT4 (aa 613-627).
    交叉反应 (详细)
    Species reactivity (expected):Canine, Pig.
    Species reactivity (tested):Human.
    纯化方法
    Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide.
    免疫原
    Peptide with sequence from the internal region (aa 613-627) of the protein sequence according to Human STAT4 (NP_003142.1.) Genename: STAT4
    Top Product
    Discover our top product STAT4 Primary Antibody
  • 应用备注
    Peptide ELISA: Limit Dilution: 1/32000. Western blot: 0.2-0.5 μg/mL. This antibody detects a band of approx. 85 kDa in transfectedHEK293 transiently expressing full-length Human STAT4 (MYC and DYKDDDDK tagged). No bands were observed in mock-transfected HEK293 and the same band was observedusing anti-myc tag antibody.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    Tris saline, pH 7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    STAT4 (Signal Transducer and Activator of Transcription 4 (STAT4))
    别名
    STAT4 (STAT4 产品)
    别名
    SLEB11 antibody, signal transducer and activator of transcription 4 antibody, STAT4 antibody, stat4 antibody, Stat4 antibody
    背景
    The STAT 4 protein is a transcription factor activated by hormone and cytokines. STAT 4 is most similar to STAT 1 (52 % ) and STAT 3 (47 %). Functionally STAT 4 is similar to other STAT family members in that it can be tyrosine phosphorylated by JAK 1 or JAK 2. STAT 4 forms homodimers and heterodimers with related STAT family members. Tyrosine phosphorylated STAT 4 can bind the interferon g activated site (GAS), and serine phosphorylation is also required for maximal transcriptional activity. STAT 4 expression is restricted to the thymus, spleen, and testis.Synonyms: Signal transducer and activator of transcription 4
    基因ID
    6775
    NCBI登录号
    NP_003142
    UniProt
    Q14765
    途径
    JAK/STAT Signaling
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