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- 抗原 See all GRIN2D 抗体
- GRIN2D (Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2D (GRIN2D))
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This GRIN2D antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 特异性
- This antibody detects endogenous levels of NMDAε4 protein. (region surrounding Pro706)
- 交叉反应 （详细）
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Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human. - 纯化方法
- Affinity Chromatography using epitope-specific immunogen.
- Top Product
- Discover our top product GRIN2D Primary Antibody
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anti-Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2D (GRIN2D) antibody
GRIN2D 适用: 人, 小鼠, 大鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2D (GRIN2D) (AA 330-480) antibodyGRIN2D 适用: 人 ELISA, WB 宿主: 兔 Polyclonal unconjugated
anti-Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2D (GRIN2D) (Internal Region) antibodyGRIN2D 适用: 人, 小鼠, 大鼠, 猴 ELISA, WB 宿主: 兔 Polyclonal unconjugated
anti-Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2D (GRIN2D) (Internal Region) antibodyGRIN2D 适用: 人, 小鼠, 大鼠 ELISA, WB, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2D (GRIN2D) (AA 671-720) antibodyGRIN2D 适用: 人, 小鼠, 大鼠 ELISA, WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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Western blot: 1: 500 - 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 浓度
- 1.0 mg/mL
- 缓冲液
- Phosphate buffered saline (PBS), pH ~7.2, 0.05 % Sodium Azide
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- 抗原
- GRIN2D (Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2D (GRIN2D))
- 别名
- NMDAR2D (GRIN2D 产品)
- 别名
- nr2d antibody, EB11 antibody, GluN2D antibody, NMDAR2D antibody, NR2D antibody, glutamate ionotropic receptor NMDA type subunit 2D antibody, glutamate receptor, ionotropic, N-methyl D-aspartate 2D antibody, glutamate receptor, ionotropic, N-methyl D-aspartate 2D L homeolog antibody, glutamate receptor, ionotropic, NMDA2D (epsilon 4) antibody, GRIN2D antibody, grin2d.L antibody, grin2d antibody, Grin2d antibody
- 背景
- Glutamate receptors mediate most excitatory neurotransmission in the brain and play an important role in neural plasticity, neural development and neurodegeneration . Ionotropic glutamate receptors are categorized into NMDA receptors and kainate/AMPA receptors, both of which contain glutamate-gated, caution-specific ion channels . Kainate/AMPA receptors are co-localized with NMDA receptors in many synapses and consist of seven structurally related subunits designated GluR-1 to -7 . The kainate/AMPA receptors are primarily responsible for the fast excitatory neurotransmission by glutamate whereas the NMDA receptors are functionally characterized by a slow kinetic and a high permeability for Ca2+ ions . The NMDA receptors consist of five subunits: epsilion 1, 2, 3, 4 and one zeta subunit . The zeta subunit is expressed throughout the brainstem, whereas the four epsilon subunits display limited distribution.Synonyms: GRIN2D, Glutamate [NMDA] receptor subunit epsilon-4, N-methyl D-aspartate receptor subtype 2D, NMDAR2D, NR2D
- 分子量
- approx. 170 kDa
- 基因ID
- 2906
- NCBI登录号
- NP_000827
- UniProt
- O15399
- 途径
- Synaptic Membrane
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