CPI-17 抗体 (pThr38)
-
- 抗原 See all CPI-17 (PPP1R14A) 抗体
- CPI-17 (PPP1R14A) (Protein Phosphatase 1, Regulatory (Inhibitor) Subunit 14A (PPP1R14A))
-
抗原表位
- pThr38
-
适用
- 人, 小鼠, 大鼠
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This CPI-17 antibody is un-conjugated
-
应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 特异性
- This antibody detects endogenous levels of CPI-17 protein only when phosphorylated at Thr38.
- 交叉反应 （详细）
-
Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human. - 纯化方法
- Affinity chromatography
- 纯度
- > 95 % by SDS-PAGE
- Top Product
- Discover our top product PPP1R14A Primary Antibody
-
anti-Protein Phosphatase 1, Regulatory (Inhibitor) Subunit 14A (PPP1R14A) (AA 30-126) antibody
PPP1R14A 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Protein Phosphatase 1, Regulatory (Inhibitor) Subunit 14A (PPP1R14A) (pThr38) antibodyPPP1R14A 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Protein Phosphatase 1, Regulatory (Inhibitor) Subunit 14A (PPP1R14A) (AA 1-147) antibodyPPP1R14A 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3A7 unconjugated
anti-Protein Phosphatase 1, Regulatory (Inhibitor) Subunit 14A (PPP1R14A) (AA 1-147), (Regulatory Subunit 14A) antibodyPPP1R14A 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Protein Phosphatase 1, Regulatory (Inhibitor) Subunit 14A (PPP1R14A) (AA 1-147) antibodyPPP1R14A 适用: 人 WB, ELISA, IF, ICC 宿主: 小鼠 Monoclonal 4H10 unconjugated
anti-Protein Phosphatase 1, Regulatory (Inhibitor) Subunit 14A (PPP1R14A) (pThr38) antibodyPPP1R14A 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 小鼠 Monoclonal AK-1F11 unconjugated
anti-Protein Phosphatase 1, Regulatory (Inhibitor) Subunit 14A (PPP1R14A) (N-Term) antibodyPPP1R14A 适用: 人, 小鼠, 大鼠, Pig WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-Protein Phosphatase 1, Regulatory (Inhibitor) Subunit 14A (PPP1R14A) (AA 5-54) antibodyPPP1R14A 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Protein Phosphatase 1, Regulatory (Inhibitor) Subunit 14A (PPP1R14A) antibodyPPP1R14A 适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Protein Phosphatase 1, Regulatory (Inhibitor) Subunit 14A (PPP1R14A) antibodyPPP1R14A 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
-
- 应用备注
-
Western Blot: 1/500 - 1/1000. Immunohistochemistry: 1/50 - 1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
-
- 浓度
- 1,0 mg/mL
- 缓冲液
- Phosphate buffered saline (PBS), pH 7.2, 0.05 % sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
-
- 抗原
- CPI-17 (PPP1R14A) (Protein Phosphatase 1, Regulatory (Inhibitor) Subunit 14A (PPP1R14A))
- 别名
- PPP1R14A (PPP1R14A 产品)
- 别名
- MGC81874 antibody, cpi-17 antibody, ppp1inl antibody, CPI-17 antibody, im:7147597 antibody, ppp1r14a antibody, zgc:110700 antibody, PPP1R14A antibody, CPI17 antibody, PPP1INL antibody, Cpi17 antibody, 1110001M11Rik antibody, protein phosphatase 1 regulatory inhibitor subunit 14A L homeolog antibody, protein phosphatase 1 regulatory inhibitor subunit 14A antibody, protein phosphatase 1, regulatory (inhibitor) subunit 14Aa antibody, protein phosphatase 1, regulatory (inhibitor) subunit 14A antibody, ppp1r14a.L antibody, ppp1r14a antibody, ppp1r14aa antibody, PPP1R14A antibody, Ppp1r14a antibody
- 背景
- CPI-17 is a phosphorylation-dependent inhibitory protein for smooth muscle Myosin phosphate. CPI-17 was originally identified as a 17 kDa PKC-potentiated inhibitory protein of protein phosphatase-1, which is dominantly expressed in smooth muscle. Phosphorylation at Threonin 38, in vitro, by PKC or Rho-kinase enhances the inhibitory potency toward myosin phosphatase. CPI-17 is also phosphorylated at Threonine 38 by protein kinase N and might be involved in the calcium sensitization of smooth muscle cont-raction as a downstream effector of Rho and/or arachidonic acid. CPI-17 is dually phosphorylated at Serine 12 and Threonine 38 by a MYPT-associated kinase, M110 kinase.Synonyms: 17 kDa PKC-potentiated inhibitory protein of PP1, CPI-17, CPI17, PPP1INL, Protein phosphatase 1 regulatory subunit 14A
- 分子量
- approx. 22 kDa
- 基因ID
- 94274
- NCBI登录号
- NP_150281
- UniProt
- Q96A00
-
