IL-8 抗体
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北京 101111
Quick Overview for IL-8 抗体 (ABIN498501)
抗原
See all IL-8 (IL8) 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- This antibody detects endogenous levels of IL-8 protein. (region surrounding Val68)
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交叉反应 （详细）
- Species reactivity (tested):Human.
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纯化方法
- Affinity chromatography
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纯度
- > 95 % by SDS-PAGE
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anti-Interleukin 8 (IL8) (AA 23-101) antibody
IL8 适用: 马 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 8 (IL8) (AA 21-99) antibodyIL8 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 8 (IL8) antibodyIL8 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal unconjugated
anti-Interleukin 8 (IL8) (AA 72-99) antibodyIL8 适用: 人 WB, IHC, ELISA, FACS, IF 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 8 (IL8) antibodyIL8 适用: 人 WB, ELISA, Neut 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 8 (IL8) (AA 72-99), (C-Term) antibodyIL8 适用: 人 WB, FACS, IF, IHC (p) 宿主: 兔 Polyclonal RB20676 unconjugated
anti-Interleukin 8 (IL8) (AA 23-101) antibodyIL8 适用: 犬 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 8 (IL8) (AA 28-99) antibodyIL8 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 8 (IL8) (AA 23-101) antibodyIL8 适用: 犬 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal C4 unconjugated
anti-Interleukin 8 (IL8) (AA 21-99) antibodyIL8 适用: 人 WB, ELISA, IP 宿主: 小鼠 Monoclonal 4G11 unconjugated
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应用备注
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Western Blot: 1/500 - 1/1000. Immunohistochemistry: 1/50 - 1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1,0 mg/mL
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缓冲液
- Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- IL-8 (IL8) (Interleukin 8 (IL8))
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别名
- Interleukin-8 / IL8
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背景
- IL-8 has been shown to function as a potent neutrophil chemostatic and activating peptide and is an important mediator of inflammatory diseases. Two distinct human IL-8 receptors, designated IL-8RA and IL-8RB, have been characterized. Both are expressed at a high level on neutrophils, and to a lesser extent on monocytes and myeloid cell lines. In addition, the IL-8RA subunit is expressed in T cells such as the Jurkat cell line. Both IL-8Rs are members of the seventransmembrane domain rhodopsin superfamily of receptors and as such, couple G proteins for signal transduction. The two receptors share 77 % amino acid identity. IL-8RA exhibits high affinity binding for IL-8 and low affinity MGSA binding, whereas IL-8RB has high affinity binding for both IL-8 and MGSA.Synonyms: CXCL8, Emoctakin, GCP1, Granulocyte chemotactic protein 1, MDNCF, MONAP, Monocyte-derived neutrophil chemotactic factor, Monocyte-derived neutrophil-activating peptide, NAP1, Neutrophil-activating protein 1, Protein 3-10C, T-cell chemotactic factor
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分子量
- approx. 38 kDa
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基因ID
- 3576
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NCBI登录号
- NP_000575
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UniProt
- P10145
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途径
- TLR signaling, Cellular Response to Molecule of Bacterial Origin, Regulation of G-Protein Coupled Receptor Protein Signaling, ER-Nucleus Signaling, Hepatitis C, Autophagy
抗原
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