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- 抗原 See all ZNF148 抗体
- ZNF148 (Zinc Finger Protein 148 (ZNF148))
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This ZNF148 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 特异性
- This antibody detects endogenous levels of ZBP-89 protein. (region surrounding Glu84)
- 交叉反应 （详细）
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Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human. - 纯化方法
- Affinity chromatography
- 纯度
- > 95 % by SDS-PAGE
- Top Product
- Discover our top product ZNF148 Primary Antibody
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anti-Zinc Finger Protein 148 (ZNF148) antibody
ZNF148 适用: 人, 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Zinc Finger Protein 148 (ZNF148) (AA 690-794) antibodyZNF148 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Zinc Finger Protein 148 (ZNF148) (N-Term) antibodyZNF148 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Zinc Finger Protein 148 (ZNF148) antibodyZNF148 适用: 人 WB, IHC, ELISA, IP 宿主: 兔 Polyclonal unconjugated
anti-Zinc Finger Protein 148 (ZNF148) (N-Term) antibodyZNF148 适用: 人 WB, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-Zinc Finger Protein 148 (ZNF148) (AA 690-794) antibodyZNF148 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Zinc Finger Protein 148 (ZNF148) (AA 106-135), (N-Term) antibodyZNF148 适用: 人 WB 宿主: 兔 Polyclonal RB40518 unconjugated
anti-Zinc Finger Protein 148 (ZNF148) (N-Term) antibodyZNF148 适用: 人, Cow WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-Zinc Finger Protein 148 (ZNF148) (N-Term) antibodyZNF148 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Zinc Finger Protein 148 (ZNF148) (AA 287-320) antibodyZNF148 适用: 斑马鱼 WB 宿主: 兔 Polyclonal RB46462 unconjugated
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- 应用备注
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Western Blot: 1/500 - 1/1000. Immunohistochemistry: 1/50 - 1/200. Immunofluorescence: 1/50 - 1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 浓度
- 1,0 mg/mL
- 缓冲液
- Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- 抗原
- ZNF148 (Zinc Finger Protein 148 (ZNF148))
- 别名
- ZNF148 (ZNF148 产品)
- 别名
- BERF-1 antibody, BFCOL1 antibody, HT-BETA antibody, ZBP-89 antibody, ZFP148 antibody, pHZ-52 antibody, 2210405J08Rik antibody, AI480666 antibody, AW045217 antibody, Znf148 antibody, Zbp-89 antibody, fb06h05 antibody, wu:fb06h05 antibody, zfp149 antibody, zgc:165342 antibody, SLC12A8 antibody, zinc finger protein 148 antibody, ZNF148 antibody, Zfp148 antibody, znf148 antibody
- 背景
- ZBP-89, also known as BFCOL1, BERF1 and ZNF 148, is a zinc finger transcription factor that is universally expressed. ZBP-89, a Kruppel-like repressor protein, is the silencer element binding factor for Vimentin. ZBP-89 has been shown to bind to GC-rich DNA elements in promoters for gastrin, ornithine decarboxylase and the cyclin-dependent kinase inhibitor p21 (also designated Cip1 or WAF1). ZBP-89 expression is induced by trans-retinoic acid or butyrate, which also induces terminal differentiation of colon cancer cells. ZBP-89 cooperates with histone acetyltransferase coactivator p300 in the regulation of p21, a cyclin-dependent kinase inhibitor whose associated gene is a target gene of p53. ZBP-89 also regulates cell proliferation, in part, through its ability to directly bind the p53 protein and retard its nuclear export. Elevated levels of ZBP-89 induce growth arrest and apoptosis in human gastrointestinal cells.Synonyms: Transcription factor ZBP-89, ZBP89, Zinc finger DNA-binding protein 89, Zinc finger protein 148
- 分子量
- approx. 89 kDa
- 基因ID
- 7707
- NCBI登录号
- NP_068799
- UniProt
- Q9UQR1
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