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- 抗原 See all Tumor Protein p73 (TP73) 抗体
- Tumor Protein p73 (TP73) (Tumor Protein P73 (TP73))
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Tumor Protein p73 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 特异性
- This antibody detects endogenous levels of p73 protein. (region surrouinding Pro298)
- 交叉反应 （详细）
- Species reactivity (tested):Human.
- 纯化方法
- Affinity chromatography
- 纯度
- > 95 % by SDS-PAGE
- Top Product
- Discover our top product TP73 Primary Antibody
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anti-Tumor Protein P73 (TP73) (acLys321) antibody
TP73 适用: 人 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Tumor Protein P73 (TP73) (Tyr221) antibodyTP73 适用: 人 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Tumor Protein P73 (TP73) (pTyr99) antibodyTP73 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Tumor Protein P73 (TP73) (AA 167-409) antibodyTP73 适用: 人 WB, IHC, IHC (p), IF 宿主: 小鼠 Monoclonal 2H5 unconjugated
anti-Tumor Protein P73 (TP73) (AA 1-198) antibodyTP73 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Tumor Protein P73 (TP73) (AA 288-317) antibodyTP73 适用: 人, 小鼠 WB, ELISA, IHC, IF, FACS 宿主: 兔 Polyclonal unconjugated
anti-Tumor Protein P73 (TP73) (AA 1-198) antibodyTP73 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Tumor Protein P73 (TP73) (AA 501-631) antibodyTP73 适用: 人, 小鼠, 大鼠 ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Tumor Protein P73 (TP73) antibodyTP73 适用: 人 WB, IHC 宿主: 兔 Monoclonal unconjugated
anti-Tumor Protein P73 (TP73) (AA 167-409) antibodyTP73 适用: 人 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 2H2 unconjugated
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- 应用备注
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Western Blot: 1/500 - 1/1000. Immunohistochemistry: 1/50 - 1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 浓度
- 1,0 mg/mL
- 缓冲液
- Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- 抗原
- Tumor Protein p73 (TP73) (Tumor Protein P73 (TP73))
- Abstract
- TP73 产品
- 别名
- P73 antibody, Trp73 antibody, TP73 antibody, tp73 antibody, Tp73 antibody, p73 antibody, TAp73 antibody, zp73theta antibody, tumor protein p73 antibody, transformation related protein 73 antibody, TP73 antibody, Tp73 antibody, tp73 antibody, Trp73 antibody
- 背景
- P73 protein is a member of the p53 family of proteins. The tumor-suppressor protein p53 exhibits sequence specific DNA binding, directly interacts with various cellular and viral proteins, and induces cell cycle arrest in response to DNA damage. In response to signals generated by a variety of genotoxic stresses, e.g, UV irradiation or DNA damage, p53 is expressed and undergoes post translational modification that results in its accumulation in the nucleus. Activation of p53 leads to cell cycle arrest and in some cases to apoptosis, resulting in the inability of genetically damaged cells to proliferate. Thus, the p53 dependent pathways help to maintain genomic stability by eliminating damaged cells. The accumulation of high levels of p53 is a potential marker for malignancy. p73 protein is expressed in either full length form (p73 alpha 80 kDa) or a shorter (p73 beta 70 kDa) mRNA variant. p73 gene was predicted to encode a protein with significant amino acid sequence similarity to p53. Each of the p53 amino acid residues implicated in direct sequence specific DNA binding is conserved in p73.Synonyms: p53-like transcription factor, p53-related protein
- 分子量
- approx. 73 kDa
- 基因ID
- 7161
- NCBI登录号
- NP_001119712
- UniProt
- O15350
- 途径
- Regulation of Cell Size, Positive Regulation of Response to DNA Damage Stimulus
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