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PER3 抗体

PER3 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN498324
发货至: 中国
  • 抗原 See all PER3 抗体
    PER3 (Period Homolog 3 (PER3))
    适用
    • 50
    • 29
    • 14
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    宿主
    • 45
    • 6
    克隆类型
    • 46
    • 5
    多克隆
    标记
    • 26
    • 3
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    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
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    This PER3 antibody is un-conjugated
    应用范围
    • 39
    • 21
    • 13
    • 13
    • 10
    • 6
    • 4
    • 3
    • 3
    • 2
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    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    特异性
    This antibody detects endogenous levels of Per3 protein. (region surrounding Pro2)
    交叉反应 (详细)
    Species reactivity (tested):Human.
    纯化方法
    Affinity Chromatography using epitope-specific immunogen.
    Top Product
    Discover our top product PER3 Primary Antibody
  • 应用备注
    Western blot 1/500-1/1000. Immunohistochemistry on Paraffin Sections: 1/50-1/200.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    Phosphate buffered saline (PBS), pH ~7.2, 0.05 % Sodium Azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    PER3 (Period Homolog 3 (PER3))
    别名
    PER3 (PER3 产品)
    别名
    period3 antibody, rper3 antibody, GIG13 antibody, 2810049O06Rik antibody, mPer3 antibody, period circadian clock 3 antibody, period circadian regulator 3 antibody, Per3 antibody, PER3 antibody
    背景
    Biological timepieces called circadian clocks are responsible for the regulation of hormonal rhythms, sleep cycles and other behaviors. The superchiasmatic nucleus (SCN), which is located in the brain, was the first mammalian circadian clock to be discovered. A number of transcription factors appearing to be molecular components of the SCN clock have been identified. Mutations within the Clock gene increase the length of the endogenous period and cause a loss of rhythmicity of circadian oscillations. Three mammalian period proteins, designated Per1, Per2 and Per3, exhibit circadian rhythyms in the SCN.During subjective night, Per1 and Per2 RNA levels increase in response to light pulses while Per3 RNA levels show no change in response to light pulses. Tim, for timeless, interacts with Per1 as well as Per2, and Tim and Per1 negatively regulate Clock-BMAL1-induced transcription.Synonyms: Cell growth-inhibiting gene 13 protein, Circadian clock protein PERIOD 3, GIG13, Period circadian protein homolog 3, hPER3
    分子量
    approx. 43 kDa
    基因ID
    8863
    NCBI登录号
    NP_058515
    UniProt
    P56645
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