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GTF2H1 抗体

GTF2H1 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN498311
发货至: 中国
  • 抗原 See all GTF2H1 抗体
    GTF2H1 (General Transcription Factor IIH, Polypeptide 1, 62kDa (GTF2H1))
    适用
    • 48
    • 30
    • 9
    • 5
    • 5
    • 5
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    人, 小鼠
    宿主
    • 52
    • 7
    克隆类型
    • 53
    • 6
    多克隆
    标记
    • 28
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This GTF2H1 antibody is un-conjugated
    应用范围
    • 50
    • 24
    • 13
    • 13
    • 9
    • 5
    • 5
    • 4
    • 4
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    特异性
    This antibody detects endogenous levels of TFIIH p62 protein. (region surrounding Ala32)
    交叉反应 (详细)
    Species reactivity (tested):Human, Mouse.
    纯化方法
    Affinity chromatography using epitope-specific immunogen
    纯度
    > 95 % (by SDS-PAGE)
    Top Product
    Discover our top product GTF2H1 Primary Antibody
  • 应用备注
    Western blot: 1: 500 - 1: 1000. Immunohistochemistry on paraffin sections: 1: 50 - 1: 200.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    Phosphate buffered saline (PBS), pH 7.2, 0.05 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
  • 抗原
    GTF2H1 (General Transcription Factor IIH, Polypeptide 1, 62kDa (GTF2H1))
    别名
    GTF2H1 / BTF2 (GTF2H1 产品)
    别名
    62kDa antibody, AW743425 antibody, AW822074 antibody, BTF2 p62 antibody, C77871 antibody, p62 antibody, GTF2H1 antibody, BTF2 antibody, P62 antibody, TFB1 antibody, TFIIH antibody, gtf2h1 antibody, MGC53309 antibody, btf2 antibody, tfiih antibody, CG8151 antibody, Dmel\\CG8151 antibody, Dmp62 antibody, TfBl antibody, l(2)06949 antibody, l(2)06950 antibody, zgc:92126 antibody, general transcription factor IIH subunit 1 antibody, general transcription factor II H, polypeptide 1 antibody, general transcription factor IIH subunit 1 L homeolog antibody, Transcription factor B1 antibody, general transcription factor IIH, polypeptide 1 antibody, GTF2H1 antibody, Gtf2h1 antibody, gtf2h1.L antibody, gtf2h1 antibody, Tfb1 antibody
    背景
    Initiation of transcription from protein-coding genes in eukaryotes is a complex process that requires RNA polymerase II, as well as families of basal transcription actors. Binding of the factor TFIID (TBP) to the TATA box is believed to be the first step in the formation of a multiprotein complex containing several additional factors, including TFIIA, TFIIB, TFIIE, TFIIF and TFII. TFIIH (or BTF2) is a multisubunit transcription/DNA repair factor that possesses several enzymatic activities. The core of TFIIH is composed of five subunits, designated p89 (XPB or ERCC3), p62, p52, p44 and p34. Additional subunits of the TFIIH complex are p80 (XPD or ERCC2) and the ternary kinase complex composed of Cdk7, cyclin H and MAT1. Both p89 and p80 have ATP-dependent helicase activity. The p62, p52 and p44 subunits have been shown to be involved in nucleotide excision repair.Synonyms: BTF2-p62, Basic transcription factor 2 62 kDa subunit, General transcription factor IIH polypeptide 1, General transcription factor IIH subunit 1, TFIIH, TFIIH basal transcription factor complex p62 subunit
    分子量
    approx. 57 kDa
    基因ID
    2965
    NCBI登录号
    NP_001135779
    UniProt
    P32780
    途径
    DNA Damage Repair
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