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- 抗原 See all Dematin (EPB49) 抗体
- Dematin (EPB49) (erythrocyte Membrane Protein Band 4.9 (Dematin) (EPB49))
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适用
- 人, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Dematin antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 特异性
- This antibody detects endogenous levels of Dematin protein.
- 交叉反应 （详细）
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Species reactivity (expected):Mouse.
Species reactivity (tested):Human. - 纯化方法
- Affinity Chromatography using epitope-specific immunogen
- Top Product
- Discover our top product EPB49 Primary Antibody
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anti-erythrocyte Membrane Protein Band 4.9 (Dematin) (EPB49) (pSer403) antibody
EPB49 适用: 人, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-erythrocyte Membrane Protein Band 4.9 (Dematin) (EPB49) (C-Term) antibodyEPB49 适用: 人, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-erythrocyte Membrane Protein Band 4.9 (Dematin) (EPB49) antibodyEPB49 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-erythrocyte Membrane Protein Band 4.9 (Dematin) (EPB49) (AA 1-383) antibodyEPB49 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-erythrocyte Membrane Protein Band 4.9 (Dematin) (EPB49) (C-Term) antibodyEPB49 适用: 人, 小鼠, Cow WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-erythrocyte Membrane Protein Band 4.9 (Dematin) (EPB49) (AA 356-405) antibodyEPB49 适用: 人, 小鼠 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-erythrocyte Membrane Protein Band 4.9 (Dematin) (EPB49) antibodyEPB49 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-erythrocyte Membrane Protein Band 4.9 (Dematin) (EPB49) (Ser345) antibodyEPB49 适用: 人, 小鼠 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-erythrocyte Membrane Protein Band 4.9 (Dematin) (EPB49) (AA 142-191) antibodyEPB49 适用: 人, Cow, 马, 犬, 豚鼠, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-erythrocyte Membrane Protein Band 4.9 (Dematin) (EPB49) (AA 356-405), (pSer403) antibodyEPB49 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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Western blot: 1/500-1/1000. Immunofluorescence: 1/50-1/200. Immunohistochemistry on Paraffin Sections: 1/50-1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 浓度
- 1.0 mg/mL
- 缓冲液
- Phosphate buffered saline (PBS) with 0.05 % sodium azide, approx. pH 7.2.
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- 抗原
- Dematin (EPB49) (erythrocyte Membrane Protein Band 4.9 (Dematin) (EPB49))
- 别名
- Dematin (EPB49 产品)
- 别名
- MGC80597 antibody, MGC108072 antibody, EPB49 antibody, DMT antibody, AI325486 antibody, Epb4.9 antibody, Epb49 antibody, dematin antibody, dematin actin binding protein L homeolog antibody, dematin actin binding protein antibody, dmtn.L antibody, DMTN antibody, dmtn antibody, Dmtn antibody
- 背景
- Caldesmon, filamin 1, nebulin, villin, plastin, ADF, gelsolin, Dematin, and cofilin are differentially expressed actin binding proteins. Dematin is a bundling protein of the erythrocyte membrane skeleton. Dematin is localized to the spectrin-actin junctions, and its actin-bundling activity is abolished upon phosphorylation by cAMP-dependent protein kinase. It may also play a role in the regulation of cell shape, implying a role in tumorigenesis. Dematin is a trimeric protein containing two subunits of 48 kDa and one subunit of 52 kDa. It is localized to the heart, brain, lung, skeletal muscle, and kidney. The Dematin gene is located on human chromosome 8p21.1, a region frequently deleted in prostate cancer, and mouse chromosome 14.Synonyms: DMT, EPB49, Erythrocyte membrane protein band 4.9
- 分子量
- approx. 50 kDa
- 基因ID
- 2039
- NCBI登录号
- NP_001107607
- UniProt
- Q08495
- 途径
- Regulation of Actin Filament Polymerization
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