电话:
400-7060-959
传真:
+86 10 56315212-8813
电子邮件:
orders@antibodies-online.cn

GABRG2 抗体 (Internal Region)

GABRG2 适用: 人, 小鼠, 大鼠, Cow WB, EIA 宿主: 山羊 Polyclonal unconjugated
产品编号 ABIN498030
发货至: 中国
  • 抗原 See all GABRG2 抗体
    GABRG2 (gamma-aminobutyric Acid (GABA) A Receptor, gamma 2 (GABRG2))
    抗原表位
    • 15
    • 8
    • 6
    • 6
    • 6
    • 6
    • 4
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 400-410, Internal Region
    适用
    • 56
    • 45
    • 43
    • 21
    • 14
    • 14
    • 10
    • 6
    • 5
    • 3
    • 3
    • 2
    • 2
    • 1
    人, 小鼠, 大鼠, Cow
    宿主
    • 60
    • 3
    • 1
    山羊
    克隆类型
    • 63
    • 1
    多克隆
    标记
    • 32
    • 4
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This GABRG2 antibody is un-conjugated
    应用范围
    • 59
    • 27
    • 16
    • 14
    • 14
    • 7
    • 5
    • 4
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    序列
    C-NNATHLQERD E
    特异性
    This antibody is expected to recognize all reported isoforms: NP_944494.1, NP_000807.2, NP_944493.2.
    交叉反应 (详细)
    Species reactivity (expected):Human, Bovine.
    Species reactivity (tested):Mouse, Rat.
    纯化方法
    Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide.
    免疫原
    Peptide with sequence from the internal region of the protein sequence according to NP_944494.1, NP_000807.2, NP_944493.2. Genename: GABRG2
    Top Product
    Discover our top product GABRG2 Primary Antibody
  • 应用备注
    Peptide ELISA: Limit Dilution: 1/16000. Western blot: 1-3 μg/mL. Approx 50 kDa band observed in Mouse and Rat Brain lysates(calculated MW of 55.0 kDa according to Mouse NP_032099.1 and 54.0 kDa according to RatNP_899156.1).
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    Tris saline, pH 7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    GABRG2 (gamma-aminobutyric Acid (GABA) A Receptor, gamma 2 (GABRG2))
    别名
    GABRG2 (GABRG2 产品)
    别名
    cae2 antibody, eca2 antibody, gabrg1 antibody, gefsp3 antibody, si:ch211-145n14.1 antibody, CAE2 antibody, ECA2 antibody, GEFSP3 antibody, GABAA-R antibody, Gabrg-2 antibody, gamma2 antibody, gamma-aminobutyric acid type A receptor gamma2 subunit antibody, gamma-aminobutyric acid (GABA) A receptor, gamma 2 antibody, gamma-aminobutyric acid type A receptor gamma 2 subunit antibody, gamma-aminobutyric acid (GABA) A receptor, subunit gamma 2 antibody, GABRG2 antibody, gabrg2 antibody, Gabrg2 antibody
    背景
    GABA A receptors are ligand-gated chloride channels that play a role as inhibitory neurotransmitters. They are known targets for certain classes of environmental and pharmaceutical compounds because a number of drugs interact with binding sites on GABA A. Some of these drugs include benzodiazepines, anticonvulsants, and anesthetics. GABA A Receptors are comprised of subunits and these are further classified into 3 major groups (alpha, beta, and gamma). The subunits determine the pharmacological characteristics. The binding of GABA to GABA A receptors results in the increase transportation of chlorine ions into the neuron. This influx results in signal transmission repression. Studies have shown that if cell to cell signaling goes unchecked due to a lack of GABA, a system "overload" can resulting in blackouts, rapid body contractions, seizures and epilepsy.Synonyms: GABA A Receptor subunit gamma-2, GABRG-2, Gamma-aminobutyric acid receptor subunit gamma-2
    基因ID
    2566
    NCBI登录号
    NP_000807
    UniProt
    P18507
You are here:
客服