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IGFBP7 抗体 (Internal Region)

IGFBP7 适用: 人, 小鼠, 大鼠 WB, EIA 宿主: 山羊 Polyclonal unconjugated
产品编号 ABIN498022
发货至: 中国
  • 抗原 See all IGFBP7 抗体
    IGFBP7 (Insulin-Like Growth Factor Binding Protein 7 (IGFBP7))
    抗原表位
    • 15
    • 6
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 145-159, Internal Region
    适用
    • 48
    • 23
    • 16
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 46
    • 4
    • 2
    • 1
    山羊
    克隆类型
    • 46
    • 6
    • 1
    多克隆
    标记
    • 27
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This IGFBP7 antibody is un-conjugated
    应用范围
    • 36
    • 20
    • 13
    • 13
    • 13
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    序列
    EKAITQVSKG TCEQG
    特异性
    Recognizes IGFBP7 (145-159).
    交叉反应 (详细)
    Species reactivity (expected):Human, Rat.
    Species reactivity (tested):Mouse.
    纯化方法
    Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide.
    免疫原
    Peptide with sequence from the internal region of the protein sequence according to NP_006423.1. Genename: IGFBP7
    Top Product
    Discover our top product IGFBP7 Primary Antibody
  • 应用备注
    Peptide ELISA: Limit Dilution: 1/8000. Western blot: 1-3 μg/mL. Approx 30 kDa band observed in Mouse Kidney lysates (calculatedMW of 29.0 kDa according to Human NP_001544.1 and to Mouse NP_032074.3).
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    Tris saline, pH 7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    IGFBP7 (Insulin-Like Growth Factor Binding Protein 7 (IGFBP7))
    别名
    IGFBP7 (IGFBP7 产品)
    别名
    zgc:85888 antibody, AGM antibody, FSTL2 antibody, IBP-7 antibody, IGFBP-7 antibody, IGFBP-7v antibody, IGFBPRP1 antibody, MAC25 antibody, PSF antibody, RAMSVPS antibody, TAF antibody, Fstl2 antibody, Mac25 antibody, insulin like growth factor binding protein 7 antibody, insulin-like growth factor binding protein 7 antibody, IGFBP7 antibody, igfbp7 antibody, Igfbp7 antibody
    背景
    IGF-BPs form high affinity complexes with both IGF-I and IGF-II and act to control of the distribution, function and activity of IGFs in various cell tissues and body fluids. There are seven named IGF-BPs. IGFBP7 plays a role in skeletal myogenesis by binding to IGF in a manner that inhibits IGF induced differentiation of skeletal myoblasts, without affecting IGF induced proliferation. Additionally, IGFBP7 suppresses growth and colony formation of prostate and breast cancer cell lines through an IGF independent mechanism, which causes a delay in the G1 phase of the cell cycle, and increased apoptosis. IGFBP7 is expressed in a wide range of normal human tissues and it usually shows reduced expression in cancer cell lines of prostate, breast, colon, and lung origin.Synonyms: IBP-7, IBP7, IGF-binding protein 7, IGFBP-7, IGFBP-rP1, Insulin-like growth factor-binding protein 7, MAC25, PGI2-stimulating factor, PSF, Prostacyclin-stimulating factor, TAF, Tumor-derived adhesion factor
    基因ID
    3490
    NCBI登录号
    NP_001544
    UniProt
    Q16270
    途径
    Growth Factor Binding
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