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HES1 抗体 (C-Term)

HES1 适用: 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3031194
发货至: 中国
  • 抗原 See all HES1 抗体
    HES1 (Hes Family bHLH Transcription Factor 1 (HES1))
    抗原表位
    • 16
    • 12
    • 8
    • 8
    • 7
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 5205-239, C-Term
    适用
    • 80
    • 50
    • 42
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    小鼠
    宿主
    • 73
    • 14
    • 1
    • 1
    克隆类型
    • 65
    • 24
    多克隆
    标记
    • 50
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This HES1 antibody is un-conjugated
    应用范围
    • 70
    • 34
    • 19
    • 14
    • 14
    • 13
    • 10
    • 6
    • 6
    • 5
    • 4
    • 3
    • 1
    • 1
    Western Blotting (WB), ELISA
    交叉反应 (详细)
    Expected species reactivity: Human, Rat
    纯化方法
    Antigen affinity purified
    免疫原
    This mouse Hes1 antibody was produced from a rabbit immunized with a KLH conjugated synthetic peptide between 205-239 amino acids from the C-terminal region of mouse Hes1.
    亚型
    Ig Fraction
    Top Product
    Discover our top product HES1 Primary Antibody
  • 应用备注
    Titration of the Hes1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:500
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    In 1X PBS, pH 7.4, with 0.09 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Aliquot the Hes1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • 抗原
    HES1 (Hes Family bHLH Transcription Factor 1 (HES1))
    别名
    Hes1 (HES1 产品)
    别名
    HES-1 antibody, HHL antibody, HRY antibody, bHLHb39 antibody, Hry antibody, HAIRY1 antibody, c-hairy1A antibody, Xhairy1 antibody, hairy1 antibody, hes1 antibody, Xhairy-1 antibody, Xlh1 antibody, hes family bHLH transcription factor 1 antibody, hairy and enhancer of split 1 (Drosophila) antibody, hes family bHLH transcription factor 4 antibody, hes family bHLH transcription factor 1 S homeolog antibody, hes family bHLH transcription factor 1 L homeolog antibody, HES1 antibody, Hes1 antibody, HES4 antibody, hes1.S antibody, hes1.L antibody
    背景
    Transcriptional repressor of genes that require a bHLH protein for their transcription. May act as a negative regulator of myogenesis by inhibiting the functions of MYOD1 and ASH1 (By similarity). Binds DNA on N-box motifs: 5'-CACNAG-3' with high affinity and on E-box motifs: 5'-CANNTG-3' with low affinity. May play a role in a functional FA core complex response to DNA cross- link damage, being required for the stability and nuclear localization of FA core complex proteins, as well as for FANCD2 monoubiquitination in response to DNA damage (By similarity).
    UniProt
    P35428
    途径
    DNA Damage Repair
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