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- 抗原 See all PINX1 抗体
- PINX1 (PIN2/TERF1 Interacting, Telomerase Inhibitor 1 (PINX1))
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PINX1 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 纯化方法
- Antigen affinity
- 免疫原
- Amino acids DHIKVQVKNNHLGLGATINNEDNWIAHQDD of human PINX1 were used as the immunogen for the PINX1 antibody.
- 亚型
- IgG
- Top Product
- Discover our top product PINX1 Primary Antibody
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anti-PIN2/TERF1 Interacting, Telomerase Inhibitor 1 (PINX1) (AA 1-100) antibody
PINX1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-PIN2/TERF1 Interacting, Telomerase Inhibitor 1 (PINX1) (Internal Region) antibodyPINX1 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-PIN2/TERF1 Interacting, Telomerase Inhibitor 1 (PINX1) (AA 85-133) antibodyPINX1 适用: 人, 小鼠, 大鼠 WB, IF (p), IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-PIN2/TERF1 Interacting, Telomerase Inhibitor 1 (PINX1) (AA 151-299) antibodyPINX1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-PIN2/TERF1 Interacting, Telomerase Inhibitor 1 (PINX1) (AA 225-237) antibodyVerified PINX1 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-PIN2/TERF1 Interacting, Telomerase Inhibitor 1 (PINX1) (N-Term) antibodyVerified PINX1 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-PIN2/TERF1 Interacting, Telomerase Inhibitor 1 (PINX1) (AA 35-84) antibodyPINX1 适用: 人, 小鼠, 大鼠, Cow, Pig, 马, 兔, 豚鼠, 猴, Bat, Hamster WB 宿主: 兔 Polyclonal unconjugated
anti-PIN2/TERF1 Interacting, Telomerase Inhibitor 1 (PINX1) (AA 107-156) antibodyPINX1 适用: 人, 小鼠, 大鼠, Cow, Pig, 马, 兔, 猴, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
anti-PIN2/TERF1 Interacting, Telomerase Inhibitor 1 (PINX1) (AA 1-221) antibodyPINX1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-PIN2/TERF1 Interacting, Telomerase Inhibitor 1 (PINX1) (AA 127-328) antibodyPINX1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Optimal dilution of the PINX1 antibody should be determined by the researcher.\. Western blot: 0.1-0.5 μg/mL
- 限制
- 仅限研究用
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- 缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
- 储存条件
- -20 °C
- 储存方法
- After reconstitution, the PINX1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
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- 抗原
- PINX1 (PIN2/TERF1 Interacting, Telomerase Inhibitor 1 (PINX1))
- 别名
- PINX1 (PINX1 产品)
- 别名
- PINX1 antibody, LPTL antibody, LPTS antibody, 2210403I16Rik antibody, 2610028A01Rik antibody, 67-11-3 antibody, AU024023 antibody, LPTS1 antibody, RGD1566025 antibody, PIN2/TERF1 interacting telomerase inhibitor 1 antibody, PIN2/TERF1 interacting, telomerase inhibitor 1 antibody, PINX1 antibody, Pinx1 antibody
- 背景
- PINX1, also known as PIN2 interacting protein 1, is a telomerase inhibitor and a possible tumor suppressor. It is mapped to 8p23. Over-expression of PINX1 results in decreased telomerase activity, telomere shortening, and induction of crisis. Reduction of PINX1 leads to an increase in telomerase activity and elongation of telomeres. PINX1 differs from other proteins that regulate telomere length in that it acts on telomerase while other proteins adjust telomere length without affecting telomerase activity. The PINX1 budding yeast orthologue Gnop1 inhibits telomerase by isolating the uncomplexed TERT protein so that it cannot associate with the telomerase template RNA, which prevents telomerase from being assembled. However, in humans, PINX1 impedes already assembled telomerase.
- UniProt
- Q96BK5
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