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LIMK2 抗体

LIMK2 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN4951617
发货至: 中国
  • 抗原 See all LIMK2 抗体
    LIMK2 (LIM Domain Kinase 2 (LIMK2))
    适用
    • 56
    • 34
    • 32
    • 2
    • 1
    • 1
    • 1
    • 1
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    • 1
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    • 1
    人, 小鼠
    宿主
    • 47
    • 3
    • 3
    • 2
    • 1
    克隆类型
    • 55
    • 1
    多克隆
    标记
    • 45
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
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    This LIMK2 antibody is un-conjugated
    应用范围
    • 47
    • 25
    • 22
    • 14
    • 10
    • 5
    • 3
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    纯化方法
    Antigen affinity
    免疫原
    Amino acids KLEDSFEALSLYLGELGIPLPAELEELDHTVSMQYGLTRD of human LIM Kinase 2 were used as the immunogen for the LIMK2 antibody.
    亚型
    IgG
    Top Product
    Discover our top product LIMK2 Primary Antibody
  • 应用备注
    Optimal dilution of the LIMK2 antibody should be determined by the researcher.\. Western blot: 0.1-0.5 μg/mL,ELISA : 0.1-0.5 μg/mL
    限制
    仅限研究用
  • 缓冲液
    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
    储存条件
    -20 °C
    储存方法
    After reconstitution, the LIMK2 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
  • 抗原
    LIMK2 (LIM Domain Kinase 2 (LIMK2))
    别名
    LIM Kinase 2 / LIMK2 (LIMK2 产品)
    别名
    xlimk2 antibody, zgc:91990 antibody, wu:fa97c09 antibody, wu:fk73e11 antibody, LIMK2 antibody, Limk2b antibody, Link2 antibody, LIMK antibody, 9430059K01 antibody, A930024P04Rik antibody, C85310 antibody, Limk2a antibody, LIM domain kinase 2 L homeolog antibody, LIM domain kinase 2 antibody, LIM motif-containing protein kinase 2 antibody, limk2.L antibody, limk2 antibody, LIMK2 antibody, Limk2 antibody
    背景
    LIM domain kinase 2 is an enzyme that in humans is encoded by the LIMK2 gene. There are approximately 40 known eukaryotic LIM proteins, so named for the LIM domains they contain. LIM domains are highly conserved cysteine-rich structures containing 2 zinc fingers. Although zinc fingers usually function by binding to DNA or RNA, the LIM motif probably mediates protein-protein interactions. LIM kinase-1 and LIM kinase-2 belong to a small subfamily with a unique combination of 2 N-terminal LIM motifs and a C-terminal protein kinase domain. The protein encoded by this gene is phosphorylated and activated by ROCK, a downstream effector of Rho, and the encoded protein, in turn, phosphorylates cofilin, inhibiting its actin-depolymerizing activity. It is thought that this pathway contributes to Rho-induced reorganization of the actin cytoskeleton. At least three transcript variants encoding different isoforms have been found for this gene.
    UniProt
    P53671
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