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LIFR 抗体

LIFR 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN4951612
发货至: 中国
  • 抗原 See all LIFR 抗体
    LIFR (Leukemia Inhibitory Factor Receptor alpha (LIFR))
    适用
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    宿主
    • 53
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    克隆类型
    • 54
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    多克隆
    标记
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    This LIFR antibody is un-conjugated
    应用范围
    • 47
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    Western Blotting (WB)
    纯化方法
    Antigen affinity
    免疫原
    Amino acids EWIKETFYPDIPNPENCKALQFQKSVCEGSSALKTLE of human LIFR were used as the immunogen for the LIFR antibody.
    亚型
    IgG
    Top Product
    Discover our top product LIFR Primary Antibody
  • 应用备注
    Optimal dilution of the LIFR antibody should be determined by the researcher.\. Western blot: 0.1-0.5 μg/mL
    限制
    仅限研究用
  • 缓冲液
    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
    储存条件
    -20 °C
    储存方法
    After reconstitution, the LIFR antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
  • 抗原
    LIFR (Leukemia Inhibitory Factor Receptor alpha (LIFR))
    别名
    LIF Receptor / LIFR (LIFR 产品)
    别名
    A230075M04Rik antibody, AW061234 antibody, LIF antibody, CD118 antibody, LIF-R antibody, SJS2 antibody, STWS antibody, SWS antibody, leukemia inhibitory factor receptor antibody, LIF receptor alpha antibody, leukemia inhibitory factor receptor alpha antibody, Lifr antibody, LOC397451 antibody, LIFR antibody
    背景
    LIFR also known as CD118 (Cluster of Differentiation 118), is a subunit of a receptor for leukemia inhibitory factor. This gene encodes a protein that belongs to the type I cytokine receptor family. This protein combines with a high-affinity converter subunit, gp130, to form a receptor complex that mediates the action of the leukemia inhibitory factor, a polyfunctional cytokine that is involved in cellular differentiation, proliferation and survival in the adult and the embryo. Mutations in this gene cause Schwartz-Jampel syndrome type 2, a disease belonging to the group of the bent-bone dysplasias. A translocation that involves the promoter of this gene, t(5,8)(p13,q12) with the pleiomorphic adenoma gene 1, is associated with salivary gland pleiomorphic adenoma, a common type of benign epithelial tumor of the salivary gland. Multiple splice variants encoding the same protein have been found for this gene.
    UniProt
    P42702
    途径
    JAK/STAT Signaling, Growth Factor Binding
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