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- 抗原 See all IDO 抗体
- IDO (Indoleamine 2,3-Dioxygenase (IDO))
- 适用
- 人, 大鼠, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This IDO antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 纯化方法
- Antigen affinity
- 免疫原
- Amino acids NDWMFIAKHLPDLIESGQLRERVEKLNMLSIDH of human IDO1 were used as the immunogen for the IDO1 antibody.
- 亚型
- IgG
- Top Product
- Discover our top product IDO Primary Antibody
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anti-Indoleamine 2,3-Dioxygenase (IDO) (AA 2-403) antibody
IDO 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Indoleamine 2,3-Dioxygenase (IDO) (AA 2-403) antibodyIDO 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal C13 unconjugated
anti-Indoleamine 2,3-Dioxygenase (IDO) (AA 106-190) antibodyIDO 适用: 大鼠 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-Indoleamine 2,3-Dioxygenase (IDO) (AA 276-360) antibodyIDO 适用: 大鼠 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-Indoleamine 2,3-Dioxygenase (IDO) (AA 26-199) antibodyIDO 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Indoleamine 2,3-Dioxygenase (IDO) (N-Term) antibodyIDO 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Optimal dilution of the IDO1 antibody should be determined by the researcher.\. Western blot: 0.1-0.5 μg/mL,IHC (Paraffin): 0.5-1 μg/mL
- 限制
- 仅限研究用
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- 缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
- 储存条件
- -20 °C
- 储存方法
- After reconstitution, the IDO1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
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- 抗原
- IDO (Indoleamine 2,3-Dioxygenase (IDO))
- 别名
- IDO1 / Indoleamine 2, 3-dioxygenase (IDO 产品)
- 别名
- IDO antibody, IDO-1 antibody, INDO antibody, Ido antibody, Indo antibody, indoleamine 2,3-dioxygenase 1 antibody, IDO1 antibody, Ido1 antibody
- 背景
- IDO1 (INDOLEAMINE 2,3-DIOXYGENASE), INDO or IDO, is an immunomodulatory enzyme produced by some alternatively activated macrophages and other immunoregulatory cells. This enzyme catalyzes the degradation of the essential amino acid L-tryptophan to N-formyl-kynurenine. By fluorescence in situ hybridization, the assignment is narrowed to chromosome 8p12-p11. INDO Interferon-gamma has an antiproliferative effect on many tumor cells and inhibits intracellular pathogens such as Toxoplasma and chlamydia, at least partly because of the induction of indoleamine 2,3-dioxygenase. During inflammation, IDO is upregulated in dendritic cells and phagocytes by proinflammatory stimuli, most notably IFNG, and the enzyme then uses superoxide as a 'cofactor' for oxidative cleavage of the indole ring of tryptophan, yielding an intermediate that deformylates to L-kynurenine.
- UniProt
- P14902
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