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- 抗原 See all FMR1 抗体
- FMR1 (Fragile X Mental Retardation 1 (FMR1))
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This FMR1 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 纯化方法
- Antigen affinity
- 免疫原
- Amino acids ENYQLVILSINEVTSKRAHMLIDMHFRSLRTKLSLIM of human FMRP were used as the immunogen for the FMRP antibody.
- 亚型
- IgG
- Top Product
- Discover our top product FMR1 Primary Antibody
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anti-Fragile X Mental Retardation 1 (FMR1) antibody
FMR1 适用: 人 WB, IHC, IF, IHC (p), FACS 宿主: 小鼠 Monoclonal 3B4 unconjugated
anti-Fragile X Mental Retardation 1 (FMR1) (AA 36-279) antibodyFMR1 适用: 人, 小鼠, 大鼠, 犬, 猴 WB, IHC, IF, IHC (p), FACS 宿主: 小鼠 Monoclonal 1C6 unconjugated
anti-Fragile X Mental Retardation 1 (FMR1) (AA 26-279) antibodyFMR1 适用: 人, 小鼠, 大鼠, 犬, 猴 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 2C3 unconjugated
anti-Fragile X Mental Retardation 1 (FMR1) (AA 121-220) antibodyFMR1 适用: 人 WB, ELISA, RNAi 宿主: 小鼠 Monoclonal 2D4 unconjugated
anti-Fragile X Mental Retardation 1 (FMR1) (AA 1-290) antibodyFMR1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Fragile X Mental Retardation 1 (FMR1) (AA 500-600) antibodyFMR1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Fragile X Mental Retardation 1 (FMR1) (AA 121-220) antibodyFMR1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3E11 unconjugated
anti-Fragile X Mental Retardation 1 (FMR1) (AA 116-130) antibodyVerified FMR1 适用: 人 WB, IHC, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Fragile X Mental Retardation 1 (FMR1) antibodyFMR1 适用: 人 WB, IHC, ELISA, ICC 宿主: 小鼠 Monoclonal 4G9 unconjugated
anti-Fragile X Mental Retardation 1 (FMR1) (AA 20-48), (N-Term) antibodyFMR1 适用: 人, 小鼠 WB, IHC (p), FACS 宿主: 兔 Polyclonal RB20964 unconjugated
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- 应用备注
- Optimal dilution of the FMRP antibody should be determined by the researcher.\. Western blot: 0.1-0.5 μg/mL
- 限制
- 仅限研究用
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- 缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
- 储存条件
- -20 °C
- 储存方法
- After reconstitution, the FMRP antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
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- 抗原
- FMR1 (Fragile X Mental Retardation 1 (FMR1))
- 别名
- FMRP / FMR1 (FMR1 产品)
- 别名
- AT24755 antibody, BcDNA:GM08679 antibody, CG6203 antibody, Dmel\\CG6203 antibody, EP(3)3517 antibody, FMR antibody, FMR1 antibody, FMRP antibody, FMRp antibody, FXR antibody, Fmrp antibody, cg6203 antibody, dFMR antibody, dFMR1 antibody, dFMRP antibody, dFXR antibody, dFXR1 antibody, dFXRP antibody, dFmr1 antibody, dFmrp antibody, dfmr antibody, dfmr1 antibody, dfxr antibody, dfxr1 antibody, dmfr1 antibody, fmr antibody, fmr1 antibody, FRAXA antibody, POF antibody, POF1 antibody, zFMR1 antibody, Fmr-1 antibody, CG6203 gene product from transcript CG6203-RC antibody, fragile X mental retardation 1 antibody, fragile X mental retardation syndrome 1 antibody, Fmr1 antibody, FMR1 antibody, fmr1 antibody
- 背景
- FMR1 (fragile X mental retardation 1) is a human gene that codes for a protein called fragile X mental retardation protein, or FMRP. This protein, most commonly found in the brain, is essential for normalcognitive developmentand female reproductive function. Mutations of this gene can lead to fragile X syndrome, mental retardation, premature ovarian failure, autism, Parkinson's disease, developmental delays and other cognitive deficits. The protein encoded by this gene binds RNA and is associated with polysomes. Additionally, the encoded protein may be involved in mRNA trafficking from the nucleus to the cytoplasm. A trinucleotide repeat (CGG) in the 5' UTR is normally found at 6-53 copies, but an expansion to 55-230 repeats is the cause of fragile X syndrome. Expansion of the trinucleotide repeat may also cause one form of premature ovarian failure (POF1). Multiple alternatively spliced transcript variants that encode different protein isoforms and which are located in different cellular locations have been described for this gene.
- UniProt
- Q06787
- 途径
- Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
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