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FMO3 抗体

FMO3 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN4951059
发货至: 中国
  • 抗原 See all FMO3 抗体
    FMO3 (Flavin Containing Monooxygenase 3 (FMO3))
    适用
    • 62
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    人, 小鼠, 大鼠
    宿主
    • 59
    • 3
    克隆类型
    • 60
    • 2
    多克隆
    标记
    • 27
    • 5
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    • 2
    • 2
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    • 2
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    • 1
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    This FMO3 antibody is un-conjugated
    应用范围
    • 49
    • 20
    • 13
    • 13
    • 10
    • 8
    • 6
    • 3
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB)
    纯化方法
    Antigen affinity
    免疫原
    Amino acids DMMNDINEKMEKKRKWFGKSETIQTDYIVY of human FMO3 were used as the immunogen for the FMO3 antibody.
    亚型
    IgG
    Top Product
    Discover our top product FMO3 Primary Antibody
  • 应用备注
    Optimal dilution of the FMO3 antibody should be determined by the researcher.\. Western blot: 0.1-0.5 μg/mL
    限制
    仅限研究用
  • 缓冲液
    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
    储存条件
    -20 °C
    储存方法
    After reconstitution, the FMO3 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
  • 抗原
    FMO3 (Flavin Containing Monooxygenase 3 (FMO3))
    别名
    FMO3 (FMO3 产品)
    别名
    MGC107820 antibody, FMOII antibody, TMAU antibody, dJ127D3.1 antibody, FM03 antibody, AW111792 antibody, flavin containing monooxygenase 3 antibody, flavin containing monooxygenase 3 L homeolog antibody, FMO3 antibody, fmo3 antibody, fmo3.L antibody, Fmo3 antibody
    背景
    FMO3 (Flavin-containing Monooxygenase 3) is an enzyme that in humans is encoded by the FMO3 gene. The mammalian flavin-containing monooxygenases (FMO) represent a multigene family whose gene products are localized in the endoplasmic reticulum of many tissues. The FMO3 gene contains 1 noncoding and 8 coding exons. And the FMO3 gene is mapped on 1q24.3. Using quantitative RNase protection assays, FMO3 is present in low abundance in fetal liver and lung and in adult kidney and lung, and in much greater abundance in adult liver. By Western blot analysis of human liver microsomal samples ranging from 8 weeks gestation to 18 years of age, FMO1 is the major fetal isoform and FMO3 is the major adult isoform. FMO3 was expressed at intermediate levels until 11 years of age when a gender-independent increase in FMO3 expression was observed during puberty. Sufferers of trimethylaminuria may display a reduced ability to metabolize substrates for FMO3 such as nicotine. FMO3 metabolizes a number of drugs, including amphetamine, clozapine, deprenyl, metamphetamine, tamoxifen, ethionamide, thiacetazone, and sulindac sulfide.
    UniProt
    P31513
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