-
- 抗原 See all FGF1 抗体
- FGF1 (Fibroblast Growth Factor 1 (Acidic) (FGF1))
-
适用
- 人, 小鼠, 大鼠
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This FGF1 antibody is un-conjugated
-
应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 纯化方法
- Antigen affinity
- 免疫原
- Amino acids F16-D155 from the human protein were used as the immunogen for the FGF-1 antibody.
- 亚型
- IgG
- Top Product
- Discover our top product FGF1 Primary Antibody
-
anti-Fibroblast Growth Factor 1 (Acidic) (FGF1) (AA 46-155) antibody
FGF1 适用: 人 WB, ELISA, IP, IF, IHC (p) 宿主: 小鼠 Monoclonal 2E12 unconjugated
anti-Fibroblast Growth Factor 1 (Acidic) (FGF1) (AA 16-155) antibodyFGF1 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Fibroblast Growth Factor 1 (Acidic) (FGF1) (AA 16-155) antibodyFGF1 适用: 大鼠 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal C3 unconjugated
anti-Fibroblast Growth Factor 1 (Acidic) (FGF1) (AA 46-155) antibodyFGF1 适用: 人 WB, ELISA, IF, PLA 宿主: 小鼠 Monoclonal 3F5 unconjugated
anti-Fibroblast Growth Factor 1 (Acidic) (FGF1) antibodyFGF1 适用: 人 WB, IF 宿主: 兔 Monoclonal unconjugated
anti-Fibroblast Growth Factor 1 (Acidic) (FGF1) (AA 16-155) antibodyFGF1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Fibroblast Growth Factor 1 (Acidic) (FGF1) (AA 5-30) antibodyFGF1 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Fibroblast Growth Factor 1 (Acidic) (FGF1) (AA 16-80) antibodyFGF1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Fibroblast Growth Factor 1 (Acidic) (FGF1) (AA 12-151) antibodyFGF1 适用: Pig WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Fibroblast Growth Factor 1 (Acidic) (FGF1) (AA 2-155) antibodyFGF1 适用: 绵羊 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
-
- 应用备注
- Optimal dilution of the FGF-1 antibody should be determined by the researcher.\. Western blot: 0.1-0.5 μg/mL,IHC (FFPE): 0.5-1 μg/mL,ELISA: 0.1-0.5 μg/mL
- 限制
- 仅限研究用
-
- 缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
- 储存条件
- -20 °C
- 储存方法
- After reconstitution, the FGF-1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
-
- 抗原
- FGF1 (Fibroblast Growth Factor 1 (Acidic) (FGF1))
- 别名
- FGF1 (FGF1 产品)
- 别名
- AFGF antibody, ECGF antibody, ECGF-beta antibody, ECGFA antibody, ECGFB antibody, FGF-1 antibody, FGF-alpha antibody, FGFA antibody, GLIO703 antibody, HBGF-1 antibody, HBGF1 antibody, Fgf1 antibody, FGF1 antibody, aFGF antibody, ecgf antibody, fgfa antibody, ecgfa antibody, ecgfb antibody, fgf-1 antibody, hbgf1 antibody, glio703 antibody, ecgf-beta antibody, fgf-alpha antibody, Dffrx antibody, Fam antibody, Fgf-1 antibody, Fgfa antibody, zgc:136885 antibody, LOC100221393 antibody, fgf1 antibody, zgc:73249 antibody, fibroblast growth factor 1 antibody, fibroblast growth factor 1 L homeolog antibody, fibroblast growth factor 1b antibody, fibroblast growth factor 1a antibody, FGF1 antibody, fgf1.L antibody, fgf1 antibody, Fgf1 antibody, fgf1b antibody, LOC100221393 antibody, fgf1a antibody
- 背景
- Fibroblast growth factor 1 (acidic) plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrin ITGAV:ITGB3. Its binding to integrin, subsequent ternary complex formation with integrin and FGFR1, and the recruitment of PTPN11 to the complex are essential for FGF1 signaling. Induces the phosphorylation and activation of FGFR1, FRS2, MAPK3/ERK1, MAPK1/ERK2 and AKT1. [UniProt]
- UniProt
- P05230
- 途径
- RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
-
You are here:
