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FcRn 抗体 (AA 54-291)

FcRn 适用: 小鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN4951007
发货至: 中国
  • 抗原 See all FcRn 抗体
    FcRn (IgG receptor FcRn (FcRn))
    抗原表位
    • 14
    • 10
    • 7
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 54-291
    适用
    • 40
    • 5
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    小鼠
    宿主
    • 38
    • 7
    • 1
    克隆类型
    • 39
    • 7
    多克隆
    标记
    • 21
    • 5
    • 5
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This FcRn antibody is un-conjugated
    应用范围
    • 29
    • 26
    • 8
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    纯化方法
    Antigen affinity
    免疫原
    Amino acids 54-291 of mouse FCGRT were used as the immunogen for the FCGRT antibody.
    亚型
    IgG
    Top Product
    Discover our top product FcRn Primary Antibody
  • 应用备注
    Optimal dilution of the FCGRT antibody should be determined by the researcher.\. Western blot: 0.1-0.5 μg/mL,IHC (Paraffin): 0.5-1 μg/mL,ELISA: suitable
    限制
    仅限研究用
  • 缓冲液
    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
    储存条件
    -20 °C
    储存方法
    After reconstitution, the FCGRT antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
  • 抗原
    FcRn (IgG receptor FcRn (FcRn))
    别名
    FCGRT (FcRn 产品)
    别名
    FCRN antibody, alpha-chain antibody, FcRn antibody, Fc fragment of IgG receptor and transporter antibody, Fc receptor, IgG, alpha chain transporter antibody, FCGRT antibody, Fcgrt antibody
    背景
    IgG receptor FcRn large subunit p51 is a protein that in humans is encoded by the FCGRT gene. This gene encodes a receptor that binds the Fc region of monomeric immunoglobulin G. The encoded protein transfers immunoglobulin G antibodies from mother to fetus across the placenta. This protein also binds immunoglobulin G to protect the antibody from degradation. In addition, it is postulated that long-range cis inactivation of the FCGRT gene is responsible for hypercatabolism of IgG in myotonic dystrophy. The FCGRT gene is closely situated to the DMPK gene, which is mutant in DM.
    UniProt
    Q61559
    途径
    Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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