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BRCA1 抗体 (pSer988)

BRCA1 适用: 人 IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN540547
发货至: 中国
  • 抗原 See all BRCA1 抗体
    BRCA1 (Breast Cancer 1 (BRCA1))
    抗原表位
    • 22
    • 18
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    • 11
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    pSer988
    适用
    • 192
    • 36
    • 25
    • 3
    • 2
    • 1
    • 1
    • 1
    宿主
    • 161
    • 37
    • 2
    克隆类型
    • 165
    • 35
    多克隆
    标记
    • 93
    • 18
    • 9
    • 7
    • 7
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    This BRCA1 antibody is un-conjugated
    应用范围
    • 126
    • 67
    • 42
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    • 41
    • 36
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    • 12
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    Immunofluorescence (IF)
    原理
    Rabbit polyclonal antibody raised against synthetic phosphopeptide of BRCA1.
    序列
    IKSpFV
    特异性
    BRCA1 (phospho-Ser988) antibody detects endogenous levels of BRCA1 only when phosphorylated at serine 988.
    交叉反应
    产品特性
    Antibody Reactive Against Synthetic Peptide.
    免疫原
    Synthetic phosphopeptide (conjugated with KLH) corresponding to residues surrounding S988 of human BRCA1.
    Top Product
    Discover our top product BRCA1 Primary Antibody
  • 应用备注
    Immunofluorescence (1:100-1:200)
    The optimal working dilution should be determined by the end user.
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    In PBS (without Mg2+ and Ca2+), 150 mM NaCl, pH 7.4 (50 % glycerol, 0.02 % sodium azide)
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Okada, Ouchi: "Cell cycle differences in DNA damage-induced BRCA1 phosphorylation affect its subcellular localization." in: The Journal of biological chemistry, Vol. 278, Issue 3, pp. 2015-20, (2003) (PubMed).

    Tutt, Ashworth: "The relationship between the roles of BRCA genes in DNA repair and cancer predisposition." in: Trends in molecular medicine, Vol. 8, Issue 12, pp. 571-6, (2002) (PubMed).

    Scully, Livingston: "In search of the tumour-suppressor functions of BRCA1 and BRCA2." in: Nature, Vol. 408, Issue 6811, pp. 429-32, (2000) (PubMed).

  • 抗原
    BRCA1 (Breast Cancer 1 (BRCA1))
    别名
    BRCA1 / RNF53 (BRCA1 产品)
    别名
    BRCAI antibody, BRCC1 antibody, BROVCA1 antibody, IRIS antibody, PNCA4 antibody, PPP1R53 antibody, PSCP antibody, RNF53 antibody, iris antibody, pscp antibody, brcai antibody, brcc1 antibody, rnf53 antibody, brca1 antibody, BRCA1 antibody, LOC100224649 antibody, BRCA1, DNA repair associated antibody, breast cancer 1 antibody, breast cancer 1, early onset antibody, breast cancer 1 L homeolog antibody, BRCA1 antibody, brca1 antibody, LOC755086 antibody, Brca1 antibody, brca1.L antibody
    基因ID
    672
    途径
    Cell Division Cycle, DNA Damage Repair, Intracellular Steroid Hormone Receptor Signaling Pathway, Positive Regulation of Response to DNA Damage Stimulus
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