ERBB3 抗体 (Tyr1328)
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- 抗原 See all ERBB3 抗体
- ERBB3 (Receptor Tyrosine-Protein Kinase ErbB-3 (ERBB3))
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抗原表位
- Tyr1328
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This ERBB3 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 原理
- Rabbit polyclonal antibody raised against synthetic peptide of ERBB3.
- 序列
- PDYWH
- 特异性
- Her3/ErbB3 (Ab-1328) Antibody detects endogenous levels of total Her3/ErbB3 protein.
- 交叉反应
- 人, 小鼠, 大鼠
- 产品特性
- Antibody Reactive Against Synthetic Peptide.
- 免疫原
- A synthetic peptide (conjugated with KLH) corresponding to residues surrounding Y1328 of human ERBB3.
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- 应用备注
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Western Blot (1:500-1:1000)
Immunohistochemistry (1:50-1:100)
Immunofluorescence (1:100-1:200)
The optimal working dilution should be determined by the end user. - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- In PBS (without Mg2+ and Ca2+), 150 mM NaCl, pH 7.4 (50 % glycerol, 0.02 % sodium azide)
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
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Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
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Activation of ErbB3-PI3-kinase pathway is correlated with malignant phenotypes of adenocarcinomas." in: Oncogene, Vol. 22, Issue 9, pp. 1294-301, (2003) (PubMed).
: "The ErbB2/ErbB3 heterodimer functions as an oncogenic unit: ErbB2 requires ErbB3 to drive breast tumor cell proliferation." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 100, Issue 15, pp. 8933-8, (2003) (PubMed).
: "Untangling the ErbB signalling network." in: Nature reviews. Molecular cell biology, Vol. 2, Issue 2, pp. 127-37, (2001) (PubMed).
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Activation of ErbB3-PI3-kinase pathway is correlated with malignant phenotypes of adenocarcinomas." in: Oncogene, Vol. 22, Issue 9, pp. 1294-301, (2003) (PubMed).
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- 抗原
- ERBB3 (Receptor Tyrosine-Protein Kinase ErbB-3 (ERBB3))
- 别名
- ERBB3 / HER3 (ERBB3 产品)
- 别名
- ErbB-3 antibody, HER3 antibody, LCCS2 antibody, MDA-BF-1 antibody, c-erbB-3 antibody, c-erbB3 antibody, erbB3-S antibody, p180-ErbB3 antibody, p45-sErbB3 antibody, p85-sErbB3 antibody, ERBB3 antibody, C76256 antibody, Erbb-3 antibody, Erbb3r antibody, Her3 antibody, nuc-ErbB3 antibody, erb-b2 receptor tyrosine kinase 3 antibody, v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) antibody, ERBB3 antibody, Erbb3 antibody
- 基因ID
- 2065
- 途径
- RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
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