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ERBB3 抗体 (Tyr1328)

ERBB3 适用: 人, 小鼠, 大鼠 WB, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN540510
发货至: 中国
  • 抗原 See all ERBB3 抗体
    ERBB3 (Receptor Tyrosine-Protein Kinase ErbB-3 (ERBB3))
    抗原表位
    • 29
    • 26
    • 21
    • 15
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    • 8
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    Tyr1328
    适用
    • 188
    • 129
    • 112
    • 17
    • 6
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
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    人, 小鼠, 大鼠
    宿主
    • 193
    • 31
    • 1
    • 1
    克隆类型
    • 190
    • 36
    多克隆
    标记
    • 116
    • 14
    • 10
    • 10
    • 10
    • 10
    • 10
    • 10
    • 6
    • 6
    • 4
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    This ERBB3 antibody is un-conjugated
    应用范围
    • 109
    • 72
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    • 31
    • 29
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    Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    原理
    Rabbit polyclonal antibody raised against synthetic peptide of ERBB3.
    序列
    PDYWH
    特异性
    Her3/ErbB3 (Ab-1328) Antibody detects endogenous levels of total Her3/ErbB3 protein.
    交叉反应
    人, 小鼠, 大鼠
    产品特性
    Antibody Reactive Against Synthetic Peptide.
    免疫原
    A synthetic peptide (conjugated with KLH) corresponding to residues surrounding Y1328 of human ERBB3.
  • 应用备注
    Western Blot (1:500-1:1000)
    Immunohistochemistry (1:50-1:100)
    Immunofluorescence (1:100-1:200)
    The optimal working dilution should be determined by the end user.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    In PBS (without Mg2+ and Ca2+), 150 mM NaCl, pH 7.4 (50 % glycerol, 0.02 % sodium azide)
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Kobayashi, Iwamatsu, Shinohara-Kanda, Ihara, Fukui: "Activation of ErbB3-PI3-kinase pathway is correlated with malignant phenotypes of adenocarcinomas." in: Oncogene, Vol. 22, Issue 9, pp. 1294-301, (2003) (PubMed).

    Holbro, Beerli, Maurer, Koziczak, Barbas, Hynes: "The ErbB2/ErbB3 heterodimer functions as an oncogenic unit: ErbB2 requires ErbB3 to drive breast tumor cell proliferation." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 100, Issue 15, pp. 8933-8, (2003) (PubMed).

    Yarden, Sliwkowski: "Untangling the ErbB signalling network." in: Nature reviews. Molecular cell biology, Vol. 2, Issue 2, pp. 127-37, (2001) (PubMed).

  • 抗原
    ERBB3 (Receptor Tyrosine-Protein Kinase ErbB-3 (ERBB3))
    别名
    ERBB3 / HER3 (ERBB3 产品)
    别名
    ErbB-3 antibody, HER3 antibody, LCCS2 antibody, MDA-BF-1 antibody, c-erbB-3 antibody, c-erbB3 antibody, erbB3-S antibody, p180-ErbB3 antibody, p45-sErbB3 antibody, p85-sErbB3 antibody, ERBB3 antibody, C76256 antibody, Erbb-3 antibody, Erbb3r antibody, Her3 antibody, nuc-ErbB3 antibody, erb-b2 receptor tyrosine kinase 3 antibody, v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) antibody, ERBB3 antibody, Erbb3 antibody
    基因ID
    2065
    途径
    RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
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