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FLT1 抗体

FLT1 适用: 大鼠, 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN4903685
发货至: 中国
  • 抗原 See all FLT1 抗体
    FLT1 (Fms-Related tyrosine Kinase 1 (VEGFR1) (FLT1))
    适用
    • 144
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    大鼠, 小鼠
    宿主
    • 141
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    克隆类型
    • 142
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    多克隆
    标记
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    This FLT1 antibody is un-conjugated
    应用范围
    • 111
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    Western Blotting (WB), Immunohistochemistry (IHC)
    产品特性
    VEGFR-1 (vascular endothelial growth factor receptor 1) is a 180- kDa membrane receptor tyrosine kinase that is the receptor for vascular endothelial growth factor (VEGF), VEGFB and PGF. VEGF is a key regulator of physiological angiogenesis during embryogenesis, skeletal growth and reproductive functions. VEGF has also been implicated in pathological angiogenesis associated with tumors, intraocular neovascular disorders and other conditions (1). VEGFR-1 has seven extracellular Ig-like domains, the second domain from the N-terminus is necessary and sufficient for high affinity VEGF binding (2). The biological effects of VEGF are mediated by VEGFR-1 and VEGFR-2 (1), and two major tyrosine phosphorylation sites at Tyr 1213 and Tyr 1242 and two minor tyrosine phosphorylation sites at Tyr 1327 and Tyr 1333 exist in VEGFR-1 (3).
    纯化方法
    Affinity purification
    免疫原
    Recombinant protein of human FLT1.
    亚型
    IgG
    Top Product
    Discover our top product FLT1 Primary Antibody
  • 应用备注
    WB 1:500-1:2000 , IHC 1:50-1:100
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.4
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze/thaw cycles.
    储存条件
    -20 °C
    储存方法
    Store at -20°C.
  • 抗原
    FLT1 (Fms-Related tyrosine Kinase 1 (VEGFR1) (FLT1))
    别名
    FLT1 (FLT1 产品)
    别名
    FLT antibody, FLT-1 antibody, VEGFR-1 antibody, VEGFR1 antibody, FLT1 antibody, flt1b antibody, sFlt1 antibody, AI323757 antibody, Flt-1 antibody, fms related tyrosine kinase 1 antibody, FMS-related tyrosine kinase 1 antibody, vascular endothelial growth factor receptor 1 antibody, fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) antibody, FMS-like tyrosine kinase 1 antibody, vascular endothelial growth factor receptor-1 antibody, FLT1 antibody, Flt1 antibody, CpipJ_CPIJ012087 antibody, flt1 antibody, FLT-1 antibody
    基因ID
    2321
    UniProt
    P17948
    途径
    RTK signaling, Signaling Events mediated by VEGFR1 and VEGFR2, VEGFR1 Specific Signals
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