Prosaposin 抗体
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- 抗原 See all Prosaposin (PSAP) 抗体
- Prosaposin (PSAP)
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Prosaposin antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunocytochemistry (ICC)
- 特异性
- Reacts with human Saposin-B
- 交叉反应 (详细)
- May cross react with proteins from other species due to sequence homology
- 纯化方法
- Purified (protein A)
- 免疫原
- Synthetic peptide derived from an internal domain of human PSAP
- Top Product
- Discover our top product PSAP Primary Antibody
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- 应用备注
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Working dilution: Optimal dilution should be determined by the end user.
The following are guidelines only :
ICC1:200 - 1:1 000 WB1:500 - 1:5 000 - 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Must be reconstituted in distilled water to reach 1 mg/mL.
- 浓度
- 1 mg/mL
- 缓冲液
- Tris 0,1M, glycine 0,1M, sucrose 2 %
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Lyophilized powder stable for a minimum of 2 years at -20°C. Store reconstituted antibodies at +4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 month from date of receipt.
- 有效期
- 24 months
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- 抗原
- Prosaposin (PSAP)
- 别名
- Proactivator Polypeptide Domain Saposin-B (PSAP) (PSAP 产品)
- 别名
- GLBA antibody, SAP1 antibody, AI037048 antibody, SGP-1 antibody, SGP1A antibody, cb759 antibody, wu:fa14a06 antibody, wu:fb36e02 antibody, wu:fb58g07 antibody, PSAP antibody, PSP-A antibody, SFTPA1B antibody, SP-A antibody, prosaposin antibody, surfactant protein A1 antibody, PSAP antibody, Psap antibody, psap antibody, LOC100011417 antibody, LOC100304726 antibody, LOC100526719 antibody, SFTPA1 antibody
- 背景
- The lysosomal degradation of sphingolipids takes place by the sequential action of specific hydrolases. Some of these enzymes require specific low-molecular mass, non-enzymic proteins: the sphingolipids activator proteins (coproteins). Saposin-A and saposin-C stimulate the hydrolysis of glucosylceramide by beta-glucosylceramidase and galactosylceramide by beta-galactosylceramidase. Saposin-C apparently acts by combining with the enzyme and acidic lipid to form an activated complex, rather than by solubilizing the substrate. Saposin-B stimulates the hydrolysis of galacto-cerebroside sulfate by arylsulfatase A, GM1 gangliosides by beta-galactosidase and globotriaosylceramide by alpha-galactosidase A. Saposin-B forms a solubilizing complex with the substrates of the sphingolipid hydrolases. Saposin-D is a specific sphingomyelin phosphodiesterase activator.
- 基因ID
- 5660
- UniProt
- P07602
- 途径
- Positive Regulation of Endopeptidase Activity
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