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Prosaposin 抗体

PSAP 适用: 人 WB, ELISA, ICC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN4889440
发货至: 中国
  • 抗原 See all Prosaposin (PSAP) 抗体
    Prosaposin (PSAP)
    适用
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    宿主
    • 43
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    克隆类型
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    多克隆
    标记
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    This Prosaposin antibody is un-conjugated
    应用范围
    • 44
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    Western Blotting (WB), ELISA, Immunocytochemistry (ICC)
    特异性
    Reacts with human Saposin-B
    交叉反应 (详细)
    May cross react with proteins from other species due to sequence homology
    纯化方法
    Purified (protein A)
    免疫原
    Synthetic peptide derived from an internal domain of human PSAP
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    Discover our top product PSAP Primary Antibody
  • 应用备注

    Working dilution: Optimal dilution should be determined by the end user.
    The following are guidelines only :
    ICC1:200 - 1:1 000 WB1:500 - 1:5 000

    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Must be reconstituted in distilled water to reach 1 mg/mL.
    浓度
    1 mg/mL
    缓冲液
    Tris 0,1M, glycine 0,1M, sucrose 2 %
    储存条件
    4 °C/-20 °C
    储存方法
    Lyophilized powder stable for a minimum of 2 years at -20°C. Store reconstituted antibodies at +4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 month from date of receipt.
    有效期
    24 months
  • 抗原
    Prosaposin (PSAP)
    别名
    Proactivator Polypeptide Domain Saposin-B (PSAP) (PSAP 产品)
    别名
    GLBA antibody, SAP1 antibody, AI037048 antibody, SGP-1 antibody, SGP1A antibody, cb759 antibody, wu:fa14a06 antibody, wu:fb36e02 antibody, wu:fb58g07 antibody, PSAP antibody, PSP-A antibody, SFTPA1B antibody, SP-A antibody, prosaposin antibody, surfactant protein A1 antibody, PSAP antibody, Psap antibody, psap antibody, LOC100011417 antibody, LOC100304726 antibody, LOC100526719 antibody, SFTPA1 antibody
    背景
    The lysosomal degradation of sphingolipids takes place by the sequential action of specific hydrolases. Some of these enzymes require specific low-molecular mass, non-enzymic proteins: the sphingolipids activator proteins (coproteins). Saposin-A and saposin-C stimulate the hydrolysis of glucosylceramide by beta-glucosylceramidase and galactosylceramide by beta-galactosylceramidase. Saposin-C apparently acts by combining with the enzyme and acidic lipid to form an activated complex, rather than by solubilizing the substrate. Saposin-B stimulates the hydrolysis of galacto-cerebroside sulfate by arylsulfatase A, GM1 gangliosides by beta-galactosidase and globotriaosylceramide by alpha-galactosidase A. Saposin-B forms a solubilizing complex with the substrates of the sphingolipid hydrolases. Saposin-D is a specific sphingomyelin phosphodiesterase activator.
    基因ID
    5660
    UniProt
    P07602
    途径
    Positive Regulation of Endopeptidase Activity
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