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- 抗原 See all TPSAB1 抗体
- TPSAB1 (Tryptase alpha/beta 1 (TPSAB1))
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抗原表位
- AA 65-275
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This TPSAB1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 原理
- Rabbit IgG polyclonal antibody for Tryptase alpha/beta-1(TPSAB1) detection. Tested with WB, IHC-P, ELISA in Human.
- 交叉反应 （详细）
- No cross reactivity with other proteins.
- 产品特性
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Rabbit IgG polyclonal antibody for Tryptase alpha/beta-1(TPSAB1) detection. Tested with WB, IHC-P, ELISA in Human.
Gene Name: tryptase alpha/beta 1
Protein Name: Tryptase alpha/beta-1 - 纯化方法
- Immunogen affinity purified.
- 免疫原
- E. coli-derived human Mast Cell Tryptase recombinant protein (Position: H65-P275). Human Mast Cell Tryptase shares 77% and 76.1% amino acid (aa) sequence identity with mouse and rat Mast Cell Tryptase, respectively.
- 亚型
- IgG
- Top Product
- Discover our top product TPSAB1 Primary Antibody
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anti-Tryptase alpha/beta 1 (TPSAB1) (AA 161-262) antibody
TPSAB1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Tryptase alpha/beta 1 (TPSAB1) (AA 161-262) antibodyTPSAB1 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal C10 unconjugated
anti-Tryptase alpha/beta 1 (TPSAB1) (AA 161-262) antibodyTPSAB1 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal C16 unconjugated
anti-Tryptase alpha/beta 1 (TPSAB1) (AA 151-275) antibodyTPSAB1 适用: 犬 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Tryptase alpha/beta 1 (TPSAB1) (AA 1-275) antibodyTPSAB1 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 2A10-B5 unconjugated
anti-Tryptase alpha/beta 1 (TPSAB1) (AA 19-210) antibodyTPSAB1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Tryptase alpha/beta 1 (TPSAB1) (AA 115-233) antibodyTPSAB1 适用: 人 IHC, StM 宿主: 小鼠 Monoclonal TPSAB1-1961 unconjugated
anti-Tryptase alpha/beta 1 (TPSAB1) (AA 149-273) antibodyTPSAB1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Tryptase alpha/beta 1 (TPSAB1) (AA 151-275) antibodyTPSAB1 适用: 犬 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal C16 unconjugated
anti-Tryptase alpha/beta 1 (TPSAB1) (AA 1-275) antibodyTPSAB1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
ELISA: Concentration: 0.1-0.5 μg/mL, Tested Species: Human
Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users. - 说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- 浓度
- 500 μg/mL
- 缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
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At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
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- 抗原
- TPSAB1 (Tryptase alpha/beta 1 (TPSAB1))
- 别名
- TPSAB1 (TPSAB1 产品)
- 背景
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Tryptase alpha-1 and tryptase beta-1 are enzymes that in humans are encoded by the same TPSAB1 gene. Tryptases comprise a family of trypsin-like serine proteases, the peptidase family S1. Tryptases are enzymatically active only as heparin-stabilized tetramers, and they are resistant to all known endogenous proteinase inhibitors. Several tryptase genes are clustered on chromosome 16p13.3. These genes are characterized by several distinct features. They have a highly conserved 3' UTR and contain tandem repeat sequences at the 5' flank and 3' UTR which are thought to play a role in regulation of the mRNA stability. In addition, these genes have an intron immediately upstream of the initiator Met codon, which separates the site of transcription initiation from protein coding sequence. This feature is characteristic of tryptases but is unusual in other genes. The alleles of this gene exhibit an unusual amount of sequence variation, such that the alleles were once thought to represent two separate genes, alpha and beta 1. Beta tryptases appear to be the main isoenzymes expressed in mast cells, whereas in basophils, alpha tryptases predominate. Tryptases have been implicated as mediators in the pathogenesis of asthma and other allergic and inflammatory disorders.
Synonyms: alpha II | Lung tryptase | MCP 7 | Pituitary tryptase | Skin tryptase | TPS 1 | TPS1 | TPS2 | TPSAB1 | TPSAB1 protein | TPSB1 | Tryptase 1 | Tryptase alpha 1 | tryptase alpha I included | Tryptase alpha II | tryptase alpha II included | tryptase alpha included | tryptase alpha/beta 1 | Tryptase beta 1 | tryptase beta I included | Tryptase I | tryptase I included | Tryptase III | Tryptase skin | Q15661 - 基因ID
- 7177
- UniProt
- Q15661
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