PIAS1 抗体 (C-Term)
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- 抗原 See all PIAS1 抗体
- PIAS1 (Protein Inhibitor of Activated STAT, 1 (PIAS1))
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抗原表位
- C-Term
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PIAS1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
- 特异性
- This antibody is specific to PIAS1 (C-term).
- 纯化方法
- Protein G Chromatography, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
- 免疫原
- This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human PIAS1.
- 亚型
- Ig Fraction
- Top Product
- Discover our top product PIAS1 Primary Antibody
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anti-Protein Inhibitor of Activated STAT, 1 (PIAS1) (AA 636-651), (C-Term) antibody
PIAS1 适用: 人, 小鼠, 大鼠 WB, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-Protein Inhibitor of Activated STAT, 1 (PIAS1) (AA 636-651) antibodyPIAS1 适用: 人, 小鼠, 大鼠 WB, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-Protein Inhibitor of Activated STAT, 1 (PIAS1) (AA 607-637) antibodyPIAS1 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Protein Inhibitor of Activated STAT, 1 (PIAS1) (N-Term) antibodyPIAS1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Protein Inhibitor of Activated STAT, 1 (PIAS1) (AA 422-651) antibodyPIAS1 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Protein Inhibitor of Activated STAT, 1 (PIAS1) (AA 543-651) antibodyPIAS1 适用: 人 WB, ELISA, PLA 宿主: 小鼠 Monoclonal 4A4 unconjugated
anti-Protein Inhibitor of Activated STAT, 1 (PIAS1) (AA 422-651) antibodyPIAS1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Protein Inhibitor of Activated STAT, 1 (PIAS1) antibodyPIAS1 适用: 人 WB 宿主: 兔 Monoclonal unconjugated
anti-Protein Inhibitor of Activated STAT, 1 (PIAS1) (N-Term) antibodyPIAS1 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Protein Inhibitor of Activated STAT, 1 (PIAS1) (AA 409-645) antibodyPIAS1 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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ELISA: 1/1,000. Western blot: 1/100-1/500. Immunohistochemistry: 1/50-1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.25 mg/mL
- 缓冲液
- PBS containing 0.09 % (W/V) Sodium Azide as preservative.
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
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- 抗原
- PIAS1 (Protein Inhibitor of Activated STAT, 1 (PIAS1))
- 别名
- PIAS1 (PIAS1 产品)
- 别名
- 2900068C24Rik antibody, Ddxbp1 antibody, GBP antibody, DDXBP1 antibody, GU/RH-II antibody, ZMIZ3 antibody, ddxbp1 antibody, gbp antibody, pias antibody, pias1-A antibody, xPAIS1 antibody, xPIAS1 antibody, zmiz3 antibody, protein inhibitor of activated STAT 1 antibody, protein inhibitor of activated STAT, 1 antibody, protein inhibitor of activated STAT, 1a antibody, protein inhibitor of activated STAT 1 L homeolog antibody, PIAS1 antibody, Pias1 antibody, pias1a antibody, pias1.L antibody
- 背景
- PIAS1 functions as an E3-type small ubiquitin-like modifier (SUMO) ligase, stabilizing the interaction between UBE2I and the substrate, and as a SUMO-tethering factor. This protein plays a crucial role in transcriptional coregulation of various cellular pathways, including the STAT pathway, the p53 pathway and the steroid hormone signaling pathway. It functions in testis as a nuclear receptor transcriptional coregulator and may have a role in androgen receptor initiation and maintenance of spermatogenesis. The effects of transcriptional coregulation, transactivation or silencing, may vary depending upon the biological context.Synonyms: DDXBP1, DEAD/H box-binding protein 1, E3 SUMO-protein ligase PIAS1, Gu-binding protein, PIAS-1, Protein inhibitor of activated STAT protein 1, RNA helicase II-binding protein
- 基因ID
- 8554, 9606
- UniProt
- O75925
- 途径
- JAK/STAT Signaling, Interferon-gamma Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Muscle Cell Differentiation, Hepatitis C
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