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IL-13 抗体

IL13 适用: Pig WB, EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN401064
发货至: 中国
  • 抗原 See all IL-13 (IL13) 抗体
    IL-13 (IL13) (Interleukin 13 (IL13))
    适用
    • 82
    • 31
    • 26
    • 6
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    Pig
    宿主
    • 73
    • 26
    • 17
    • 2
    • 2
    克隆类型
    • 77
    • 43
    多克隆
    标记
    • 69
    • 16
    • 9
    • 6
    • 5
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This IL-13 antibody is un-conjugated
    应用范围
    • 86
    • 69
    • 32
    • 17
    • 16
    • 13
    • 13
    • 12
    • 10
    • 10
    • 10
    • 8
    • 7
    • 6
    • 5
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    特异性
    This antibody reacts to Interleukin-13.
    交叉反应 (详细)
    Species reactivity (expected):Sheep, Dolphin, Beluga, Bovine, Human, Certain monkey, Dusky titi, Macaque, Baboon, Mangabey, Canine, Llama, Camel, Galago, Horse, Rat, Mouse, Gerbil.
    Species reactivity (tested):Porcine.
    纯化方法
    Affinity chromatography on Protein A
    免疫原
    Full length recombinant protein raised in yeast, corresponding to mature swine IL-13 protein
    亚型
    IgG
    Top Product
    Discover our top product IL13 Primary Antibody
  • 应用备注
    ELISA: 1/11,000. Western Blot: 1.5 - 2 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 状态
    Liquid
    溶解方式
    Restore with 100 μL of deionized water or equivalent.
    浓度
    1.0 mg/mL by UV absorbance at 280 nm
    缓冲液
    0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2 containing 0.01 % (w/v) Sodium Azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Prior to reconstitution store at 2-8 °C. Following reconstitution store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
  • 抗原
    IL-13 (IL13) (Interleukin 13 (IL13))
    别名
    Interleukin-13 / IL13 (IL13 产品)
    别名
    IL13 antibody, IL-13 antibody, P600 antibody, Il-13 antibody, L13 antibody, interleukin 13 antibody, IL13 antibody, Il13 antibody
    背景
    Interleukin 13 (IL-13), of the IL-4 superfamily, is a cytokine secreted by many cell types, but especially T helper type 2 (Th2) cells, that is an important mediator of allergic inflammation and disease. IL-13 induces its effects through a multi-subunit receptor that includes the alpha chain of the IL-4 receptor (IL-4Ra) and at least one IL-13-specific binding chain. Most of the biological effects of IL-13, like those of IL-4, are linked to a single transcription factor, STAT6. In humans, IL-13 can induce immunoglobulin E (IgE) secretion from activated B cells. In mice, deletion of IL-13 does not markedly affect either Th2 cell development or antigen-specific IgE responses induced by potent allergens. Deletion of IL-4 abrogates these responses. IL-13 acts as a molecular bridge linking allergic inflammatory cells to the non-immune cells in contact with them, thus altering physiological function. Although IL-13 is associated primarily with the induction of airway disease, including airway hyperresponsiveness, goblet cell metaplasia and mucus hypersecretion, it also induces airway matrix metalloproteinases as part of a mechanism that protects against excessive allergic inflammation that predisposes to asphyxiation.Synonyms: IL-13, NC30
    基因ID
    396721
    NCBI登录号
    NP_998968
    UniProt
    Q95J68
    途径
    JAK/STAT Signaling, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Proton Transport
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