AGT 抗体 (N-Term)
Quick Overview for AGT 抗体 (N-Term) (ABIN392327)
抗原
See all AGT 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 37-65, N-Term
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纯化方法
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
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免疫原
- This AGT antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 37-65 amino acids from the N-terminal region of human AGT.
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亚型
- Ig Fraction
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anti-Angiotensinogen (serpin Peptidase Inhibitor, Clade A, Member 8) (AGT) antibody
AGT 适用: 人 WB, ICC, IHC (p), IF 宿主: 兔 Polyclonal unconjugated
anti-Angiotensinogen (serpin Peptidase Inhibitor, Clade A, Member 8) (AGT) (AA 23-477) antibodyAGT 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Angiotensinogen (serpin Peptidase Inhibitor, Clade A, Member 8) (AGT) (AA 25-477) antibodyAGT 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Angiotensinogen (serpin Peptidase Inhibitor, Clade A, Member 8) (AGT) (AA 376-485) antibodyAGT 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1A10 unconjugated
anti-Angiotensinogen (serpin Peptidase Inhibitor, Clade A, Member 8) (AGT) (AA 25-477) antibodyAGT 适用: 大鼠 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal C17 unconjugated
anti-Angiotensinogen (serpin Peptidase Inhibitor, Clade A, Member 8) (AGT) (AA 44-427) antibodyAGT 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Angiotensinogen (serpin Peptidase Inhibitor, Clade A, Member 8) (AGT) antibodyAGT 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Angiotensinogen (serpin Peptidase Inhibitor, Clade A, Member 8) (AGT) (AA 35-285) antibodyAGT 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Angiotensinogen (serpin Peptidase Inhibitor, Clade A, Member 8) (AGT) (AA 1-485) antibodyAGT 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 3C10 unconjugated
anti-Angiotensinogen (serpin Peptidase Inhibitor, Clade A, Member 8) (AGT) antibodyAGT 适用: 激素 WB, ICC, IHC (p), IF 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:1000. IHC-P: 1:10~50
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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有效期
- 6 months
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- AGT (Angiotensinogen (serpin Peptidase Inhibitor, Clade A, Member 8) (AGT))
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别名
- AGT
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背景
- AGT, pre-angiotensinogen or angiotensinogen precursor, is expressed in the liver and is cleaved by the enzyme renin in response to lowered blood pressure. The resulting product, angiotensin I, is then cleaved by angiotensin converting enzyme (ACE) to generate the physiologically active enzyme angiotensin II. The protein is involved in maintaining blood pressure and in the pathogenesis of essential hypertension and preeclampsia. Mutations in AGT gene are associated with susceptibility to essential hypertension, and can cause renal tubular dysgenesis, a severe disorder of renal tubular development. Defects in AGT gene have also been associated with non-familial structural atrial fibrillation, and inflammatory bowel disease.
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分子量
- 53154
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基因ID
- 183
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NCBI登录号
- NP_000020
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UniProt
- P01019
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途径
- JAK/STAT Signaling, ACE Inhibitor Pathway, EGFR Signaling Pathway, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Regulation of Lipid Metabolism by PPARalpha, Protein targeting to Nucleus, Feeding Behaviour, Monocarboxylic Acid Catabolic Process, Dicarboxylic Acid Transport, Positive Regulation of Response to DNA Damage Stimulus, Regulation of long-term Neuronal Synaptic Plasticity
抗原
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