LATS1 抗体 (N-Term)
(1 reference)-
- 抗原 See all LATS1 抗体
- LATS1 (LATS, Large Tumor Suppressor, Homolog 1 (Drosophila) (LATS1))
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抗原表位
- AA 1-30, N-Term
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This LATS1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 纯化方法
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
- 免疫原
- This LATS1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human LATS1.
- 克隆位点
- RB3029
- 亚型
- Ig Fraction
- Top Product
- Discover our top product LATS1 Primary Antibody
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anti-LATS, Large Tumor Suppressor, Homolog 1 (Drosophila) (LATS1) (AA 1-280) antibody
LATS1 适用: 人 ELISA, IHC, IP, IF 宿主: 兔 Polyclonal unconjugated
anti-LATS, Large Tumor Suppressor, Homolog 1 (Drosophila) (LATS1) (AA 521-620) antibodyLATS1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3A7 unconjugated
anti-LATS, Large Tumor Suppressor, Homolog 1 (Drosophila) (LATS1) (Internal Region) antibodyLATS1 适用: 人, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-LATS, Large Tumor Suppressor, Homolog 1 (Drosophila) (LATS1) (pThr1079) antibodyLATS1 适用: 人, 小鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-LATS, Large Tumor Suppressor, Homolog 1 (Drosophila) (LATS1) (AA 1-30) antibodyLATS1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-LATS, Large Tumor Suppressor, Homolog 1 (Drosophila) (LATS1) (pThr1041), (pThr1079) antibodyLATS1 适用: 人, 小鼠 IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-LATS, Large Tumor Suppressor, Homolog 1 (Drosophila) (LATS1) (AA 1-1130) antibodyLATS1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-LATS, Large Tumor Suppressor, Homolog 1 (Drosophila) (LATS1) (AA 971-1020) antibodyLATS1 适用: 人, 小鼠, 大鼠, 犬, 马, 猴, Cow, 兔, 斑马鱼, Bat, Hamster WB 宿主: 兔 Polyclonal unconjugated
anti-LATS, Large Tumor Suppressor, Homolog 1 (Drosophila) (LATS1) (Middle Region) antibodyLATS1 适用: 人, 小鼠, 大鼠, 犬, 马, Cow, 兔, 斑马鱼, Saccharomyces cerevisiae, 绵羊 WB 宿主: 兔 Polyclonal unconjugated
anti-LATS, Large Tumor Suppressor, Homolog 1 (Drosophila) (LATS1) (N-Term) antibodyLATS1 适用: 人, 小鼠, 大鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB: 1:1000. IHC-P: 1:50~100
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
- 有效期
- 6 months
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: "Identification of novel posttranscriptional targets of the BCR/ABL oncoprotein by ribonomics: requirement of E2F3 for BCR/ABL leukemogenesis." in: Blood, Vol. 111, Issue 2, pp. 816-28, (2008) (PubMed).
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: "Identification of novel posttranscriptional targets of the BCR/ABL oncoprotein by ribonomics: requirement of E2F3 for BCR/ABL leukemogenesis." in: Blood, Vol. 111, Issue 2, pp. 816-28, (2008) (PubMed).
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- 抗原
- LATS1 (LATS, Large Tumor Suppressor, Homolog 1 (Drosophila) (LATS1))
- 别名
- LATS1 (LATS1 产品)
- 别名
- WARTS antibody, wts antibody, AW208599 antibody, Lats antibody, si:dkey-181i3.5 antibody, wu:fc19a11 antibody, zgc:123219 antibody, lats1 antibody, RGD1564085 antibody, warts antibody, large tumor suppressor kinase 1 antibody, large tumor suppressor antibody, large tumor suppressor kinase 1 S homeolog antibody, LATS1 antibody, Lats1 antibody, lats1 antibody, lats1.S antibody
- 背景
- The protein encoded by this gene is a putative serine/threonine kinase that localizes to the mitotic apparatus and complexes with cell cycle controller CDC2 kinase in early mitosis. The protein is phosphorylated in a cell-cycle dependent manner, with late prophase phosphorylation remaining through metaphase. The N-terminal region of the protein binds CDC2 to form a complex showing reduced H1 histone kinase activity, indicating a role as a negative regulator of CDC2/cyclin A. In addition, the C-terminal kinase domain binds to its own N-terminal region, suggesting potential negative regulation through interference with complex formation via intramolecular binding. Biochemical and genetic data suggest a role as a tumor suppressor. This is supported by studies in knockout mice showing development of soft-tissue sarcomas, ovarian stromal cell tumors and a high sensitivity to carcinogenic treatments.
- 分子量
- 126870
- 基因ID
- 9113
- NCBI登录号
- NP_001257448, NP_004681
- UniProt
- O95835
- 途径
- Regulation of Actin Filament Polymerization, Maintenance of Protein Location
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