ZMIZ1 抗体 (C-Term)
(3 references)-
- 抗原 See all ZMIZ1 抗体
- ZMIZ1 (Zinc Finger, MIZ-Type Containing 1 (ZMIZ1))
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抗原表位
- AA 1038-1067, C-Term
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This ZMIZ1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 预测反应
- M
- 纯化方法
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
- 免疫原
- This RAI17 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1038-1067 amino acids from the C-terminal region of human RAI17.
- 克隆位点
- RB1963
- 亚型
- Ig Fraction
- Top Product
- Discover our top product ZMIZ1 Primary Antibody
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anti-Zinc Finger, MIZ-Type Containing 1 (ZMIZ1) (AA 405-559) antibody
ZMIZ1 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Zinc Finger, MIZ-Type Containing 1 (ZMIZ1) (C-Term) antibodyZMIZ1 适用: 人 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Zinc Finger, MIZ-Type Containing 1 (ZMIZ1) (N-Term) antibodyZMIZ1 适用: 人, 小鼠, 大鼠, 犬, 斑马鱼, Cow, 豚鼠, 马, 兔, 非洲爪蟾, Bat, 猴, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Zinc Finger, MIZ-Type Containing 1 (ZMIZ1) (N-Term) antibodyZMIZ1 适用: 人, 小鼠, 大鼠, 犬, 斑马鱼, Cow, 豚鼠, 马, 兔 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB: 1:2000. IHC-P: 1:50~100
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
- 有效期
- 6 months
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: "Identification of Two Additional Susceptibility Loci for Inflammatory Bowel Disease in a Chinese Population." in: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, Vol. 41, Issue 5, pp. 2077-2090, (2017) (PubMed).
: "The PIAS-like Coactivator Zmiz1 Is a Direct and Selective Cofactor of Notch1 in T Cell Development and Leukemia." in: Immunity, Vol. 43, Issue 5, pp. 870-83, (2015) (PubMed).
: "Convergence of the ZMIZ1 and NOTCH1 pathways at C-MYC in acute T lymphoblastic leukemias." in: Cancer research, Vol. 73, Issue 2, pp. 930-41, (2013) (PubMed).
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: "Identification of Two Additional Susceptibility Loci for Inflammatory Bowel Disease in a Chinese Population." in: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, Vol. 41, Issue 5, pp. 2077-2090, (2017) (PubMed).
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- 抗原
- ZMIZ1 (Zinc Finger, MIZ-Type Containing 1 (ZMIZ1))
- 别名
- RAI17 (ZMIZ1 产品)
- 别名
- miz antibody, rai17 antibody, zimz1 antibody, zimp10 antibody, hzimp10 antibody, MIZ antibody, RAI17 antibody, TRAFIP10 antibody, ZIMP10 antibody, hZIMP10 antibody, BC065120 antibody, E330020C23 antibody, ENSMUSG00000072684 antibody, Gm10397 antibody, I920194n01 antibody, Rai17 antibody, Zimp10 antibody, wu:fb80e10 antibody, zgc:175159 antibody, zmiz1 antibody, zinc finger MIZ-type containing 1 antibody, zinc finger, MIZ-type containing 1 antibody, zinc finger, MIZ-type containing 1a antibody, ZMIZ1 antibody, zmiz1 antibody, Zmiz1 antibody, zmiz1a antibody
- 背景
- Retinoic acid plays a critical role in development, cellular growth, and differentiation and induces the expression of a variety of genes. RAI17 expression is induced by retinoic acid and is predominantly expressed in heart, brain and ovaries. Within brain, highest expression is in amygdala. The deduced 1,067-amino acid protein contains an MSX-interacting zinc finger (MIZ) domain, a nuclear localization signal sequence, and 2 proline-rich regions. A strong intrinsic transactivation domain is identified in the C-terminal proline-rich region. RAI17 expression is detected in various cancer cell lines. RAI17 colocalizes with endogenous androgen receptor (AR) in the nuclei of prostate epithelial cells from human tissue samples. In human prostate cancer cells, RAI17 increases the transcriptional activity of AR. Studies using sumoylation-deficient AR mutants suggest that the increase of AR activity by RAI17 is dependent upon receptor sumoylation.
- 分子量
- 115483
- 基因ID
- 57178
- NCBI登录号
- NP_065071
- UniProt
- Q9ULJ6
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