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FCER2 抗体

FCER2 适用: 小鼠 FACS 宿主: 大鼠 Monoclonal 2G8 unconjugated
产品编号 ABIN376377
发货至: 中国
  • 抗原 See all FCER2 抗体
    FCER2 (Fc Fragment of IgE, Low Affinity II, Receptor For (CD23) (FCER2))
    适用
    • 97
    • 50
    • 11
    小鼠
    宿主
    • 57
    • 46
    • 16
    大鼠
    克隆类型
    • 75
    • 42
    • 2
    单克隆
    标记
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    This FCER2 antibody is un-conjugated
    应用范围
    • 72
    • 51
    • 32
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    Flow Cytometry (FACS)
    特异性
    Mouse CD23, Mr 45-49 kDa
    产品特性
    Rat Anti-Mouse CD23-LE/AF
    纯化方法
    Purified
    内毒素水平
    Low endotoxin
    免疫原
    FcR isolated from B cell lymphoma cell line M12.4.5
    克隆位点
    2G8
    亚型
    IgG2a
    Top Product
    Discover our top product FCER2 Primary Antibody
  • 应用备注
    • Applications: FC - Quality tested , IHC-FS - Reported in literature , ELISA - Reported in literature
    • Working Dilutions: Flow Cytometry Purified (UNLB) antibody 1 g/106 cells FITC and BIOT conjugates 1 g/106 cells PE, APC, and PE/CY7 conjugates 0.1 g/106 cells For flow cytometry, the suggested use of these reagents is in a final volume of 100 L
    说明

    cell sorting

    样本量
    1 mL
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    0.5 mg of purified immunoglobulin in 1.0 mL of PBS
    储存液
    Azide free
    注意事项
    Each reagent is stable for the period shown on the bottle label if stored as directed.
    储存条件
    -20 °C
    储存方法
    Aliquot and freeze the low endotoxin, azide-free product at -20 °C immediately upon receipt.
  • 抗原
    FCER2 (Fc Fragment of IgE, Low Affinity II, Receptor For (CD23) (FCER2))
    别名
    CD23 (FCER2 产品)
    别名
    BLAST-2 antibody, CD23 antibody, CD23A antibody, CLEC4J antibody, FCE2 antibody, IGEBF antibody, Fcer2a antibody, Fc fragment of IgE receptor II antibody, FCER2 antibody, Fcer2 antibody
    背景
    The CD23 antigen is the low affinity IgE Fc receptor, which is a 49 kDa protein with 38 and 28 kDa fragments. It is expressed on most mature, conventional B cells (but not on peritoneal CD5 + B cells), and can also be found on the surface of T cells, macrophages and platelets. It is distinct from the high affinity IgE receptors found on basophils and mast cells, which mediate allergic reactions. The low affinity receptors are thought to play a role in isotype specific immunoregulation. The regulation of CD23 surface expression appears to be integral with the complex IgE system, which involves interactions of cells, cytokines, antibodies and regulatory factors. CD23 has been described as a membrane bound cytokine, in that the soluble cleavage products of CD23 are themselves able to act as cytokines in vitro.
    途径
    Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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