MHC, Class I 抗体
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北京 101111
Quick Overview for MHC, Class I 抗体 (ABIN371396)
抗原
See all MHC, Class I 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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产品特性
- Synonyms: MHC class I-alpha, Major Histocompatibility Complex Class I
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纯化方法
- Purified
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亚型
- IgG1
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应用备注
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Flow Cytometry. (Ref.1-4)Immunoprecipitation. (Ref.1-3)Immunohistochemistry on Frozen Sections. Western Blot. Immunoaffinity Chromatography.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 0.5 mg/mL
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缓冲液
- 100 mM Borate Buffered Saline, pH 8.2. No preservatives or amine-containing buffer salts added.
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储存条件
- 4 °C/-20 °C
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储存方法
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Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch. -
有效期
- 12 months
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- MHC, Class I
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别名
- MHC Class I
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背景
- MHC Class I molecules play a central role in the immune system by presenting peptides derived from the endoplasmic reticulum lumen. MHC class I antigens are heterodimers consisting of one alpha chain (44 kDa) with beta 2 microglobulin (11.5 kDa). The antigen is expressed by all somatic cells at varying levels. MHC Class I molecules are expressed on most nucleated cells where they present endogenously synthesized antigenic peptides to CD8+ T lymphocytes, which are usually cytotoxic T cells. (Ref.1-3)Fibroblasts or neurons however only show a low level of antigen.Synonyms: HLA Class 1, MHC Class 1, Major Histocompatibility complex class I
抗原
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