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小鼠 anti-小鸡 IgM Antibody

FACS, IF, Func Monoclonal M-4 IgM unconjugated
产品编号 ABIN371376
发货至: 中国
  • 抗原 See all IgM products
    IgM
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    小鼠
    克隆类型
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    单克隆
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    Flow Cytometry (FACS), Immunofluorescence (IF), Functional Studies (Func)
    纯化方法
    Purified
    克隆位点
    M-4
    亚型
    IgM
  • 应用备注
    Flow Cytometry: < / = 1 μg/10^6 cells. Indirect Immunofluorescence staining. In ovo suppression of chicken B lymphocytes. In vitro activation of Chicken peripheral B lymphocytes

    Other applications not tested.
    Otimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    100 mM Borate Buffered Saline, pH 8.2. No preservatives or amine-containing buffer salts added.
    储存液
    Without preservative
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -28 °C for longer.
  • 抗原
    IgM
    Abstract
    IgM 产品
    物质类
    Antibody
    背景
    IgM normally constitutes about 10 % of serum immunoglobulins. IgM antibody is prominent in early immune responses to most antigens and is largely confined to plasma due to it's large size. Monomeric IgM is expressed as a membrane bound antibody on the surface of B cells and as a pentamer when secreted by plasma cells. Due to it's high valency IgM is more efficient than other isotypes is binding antigens with repeating epitopes (virus particles and red blood cells) and is more efficient than IgG in activiating the complement pathway. The gene for the mu constant region contains four domains separated by short intervening sequences. IgM measurement yields information about the body's immediate resistance and response to infection as well as information related to specific diseases. Decreased levels are associated with immune deficiency states, hereditary deficiencies, and myeloma. Increased levels can be associated with Waldenstrom's macroglobulinemia, chronic infection and hepatocellular disease.Synonyms: Chicken Immunoglobulin M
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