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ICAM1 抗体 (AA 510-514)

ICAM1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN362683
发货至: 中国
  • 抗原 See all ICAM1 抗体
    ICAM1 (Intercellular Adhesion Molecule 1 (ICAM1))
    抗原表位
    • 18
    • 16
    • 16
    • 8
    • 7
    • 6
    • 5
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 510-514
    适用
    • 209
    • 80
    • 38
    • 7
    • 5
    • 5
    • 4
    • 3
    • 1
    • 1
    宿主
    • 120
    • 108
    • 27
    • 4
    • 1
    • 1
    • 1
    克隆类型
    • 140
    • 119
    • 1
    多克隆
    标记
    • 121
    • 26
    • 23
    • 18
    • 9
    • 5
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ICAM1 antibody is un-conjugated
    应用范围
    • 166
    • 150
    • 62
    • 61
    • 45
    • 40
    • 35
    • 35
    • 28
    • 28
    • 25
    • 20
    • 12
    • 10
    • 6
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    特异性
    The antibody detects endogenous level of total ICAM-1 protein.
    纯化方法
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography usingepitope-specific immunogen.
    免疫原
    Peptide sequence around AA 510-514 (K-K-Y-R-L) derived from Human ICAM-1. Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates.
    亚型
    IgG
    Top Product
    Discover our top product ICAM1 Primary Antibody
  • 应用备注
    Western blotting: 1:500-1:1000  
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C/-20 °C
    储存方法
    Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
  • Wang, Zhang, Yan, Zhao, Zhou, Wang, Lu, Zhang: "Impaired CD200-CD200R-mediated microglia silencing enhances midbrain dopaminergic neurodegeneration: roles of aging, superoxide, NADPH oxidase, and p38 MAPK." in: Free radical biology & medicine, Vol. 50, Issue 9, pp. 1094-106, (2011) (PubMed).

    Ould-yahoui, Tremblay, Sbai, Ferhat, Bernard, Charrat, Gueye, Lim, Brew, Risso, Dive, Khrestchatisky, Rivera: "A new role for TIMP-1 in modulating neurite outgrowth and morphology of cortical neurons." in: PLoS ONE, Vol. 4, Issue 12, pp. e8289, (2009) (PubMed).

    Sbai, Ould-Yahoui, Ferhat, Gueye, Bernard, Charrat, Mehanna, Risso, Chauvin, Fenouillet, Rivera, Khrestchatisky: "Differential vesicular distribution and trafficking of MMP-2, MMP-9, and their inhibitors in astrocytes." in: Glia, Vol. 58, Issue 3, pp. 344-66, (2009) (PubMed).

  • 抗原
    ICAM1 (Intercellular Adhesion Molecule 1 (ICAM1))
    别名
    ICAM-1 (ICAM1 产品)
    别名
    BB2 antibody, CD54 antibody, P3.58 antibody, Icam-1 antibody, Ly-47 antibody, MALA-2 antibody, ICAM antibody, ICAM-1 antibody, ICAM1 antibody, intercellular adhesion molecule 1 antibody, intercellular adhesion molecule-1 antibody, ICAM1 antibody, Icam1 antibody, ICAM-1 antibody
    物质类
    Viral Protein
    背景
    ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin a-L/beta-2). During leukocyte trans-endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through SGEF and RHOG activation. In case of rhinovirus infection acts as a cellular receptor for the virus.
    分子量
    92 kDa
    NCBI登录号
    NP_000192
    UniProt
    P05362
    途径
    Cellular Response to Molecule of Bacterial Origin, Regulation of Actin Filament Polymerization, Carbohydrate Homeostasis, Regulation of Leukocyte Mediated Immunity, Thromboxane A2 Receptor Signaling
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