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ErbB2/Her2 抗体 (AA 875-879)

ErbB2/Her2 适用: 人, 小鼠, 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN362616
发货至: 中国
  • 抗原 See all ErbB2/Her2 抗体
    ErbB2/Her2 (Receptor tyrosine-protein kinase erbB-2 (ErbB2/Her2))
    抗原表位
    • 32
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    AA 875-879
    适用
    • 509
    • 186
    • 163
    • 34
    • 10
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    • 5
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    • 3
    • 2
    • 1
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    人, 小鼠, 大鼠
    宿主
    • 408
    • 148
    • 11
    • 5
    • 3
    • 3
    克隆类型
    • 411
    • 164
    • 2
    多克隆
    标记
    • 266
    • 46
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    This ErbB2/Her2 antibody is un-conjugated
    应用范围
    • 296
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    • 139
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    • 66
    • 50
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    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
    特异性
    The antibody detects endogenous level of total HER2 protein.
    纯化方法
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography usingepitope-specific immunogen.
    免疫原
    Peptide sequence around AA 875-879 (T-E-Y-H-A) derived from Human HER2. Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates.
    亚型
    IgG
    Top Product
    Discover our top product ErbB2/Her2 Primary Antibody
  • 应用备注
    Western blotting: 1:500-1:1000
    Immunohistochemistry: 1:50-1:100
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C/-20 °C
    储存方法
    Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
  • Li, Bu, Wu, Wu, Huang: "The "HER2-PI3K/Akt-FASN Axis" regulated malignant phenotype of colorectal cancer cells." in: Lipids, Vol. 47, Issue 4, pp. 403-11, (2012) (PubMed).

  • 抗原
    ErbB2/Her2 (Receptor tyrosine-protein kinase erbB-2 (ErbB2/Her2))
    别名
    HER2 (ErbB2/Her2 产品)
    别名
    CD340 antibody, HER-2 antibody, HER-2/neu antibody, HER2 antibody, MLN 19 antibody, NEU antibody, NGL antibody, TKR1 antibody, Erbb-2 antibody, Neu antibody, c-erbB2 antibody, c-neu antibody, mKIAA3023 antibody, wu:fv70f10 antibody, zgc:63601 antibody, erb2 antibody, erb-b2 receptor tyrosine kinase 2 antibody, ERBB2 antibody, Erbb2 antibody, erbb2 antibody
    背景
    Essential component of a neuregulin-receptor complex, although neuregulins do not interact with it alone. GP30 is a potential ligand for this receptor. Not activated by EGF, TGF-a and amphiregulin.
    分子量
    185 kDa
    UniProt
    P04626
    途径
    RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Skeletal Muscle Fiber Development
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