ABL1/2 抗体 (pTyr393, pTyr429)
ABL1/ABL2
适用: 人, 小鼠
IHC, IF
宿主: 兔
Polyclonal
unconjugated
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- 抗原 See all ABL1/2 (ABL1/ABL2) 抗体
- ABL1/2 (ABL1/ABL2) (Abelson Murine Leukemia Viral Oncogene Homolog 1/2 (ABL1/ABL2))
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抗原表位
- pTyr393, pTyr429
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适用
- 人, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This ABL1/2 antibody is un-conjugated
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应用范围
- Immunohistochemistry (IHC), Immunofluorescence (IF)
- 特异性
- The antibody detects endogenous level of ABL1/2 only when phosphorylated at tyrosine393/429.
- 纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography usingepitope-specific phosphopeptide. The antibody against non-phosphopeptide was removedby chromatography using non-phosphopeptide corresponding to the phosphorylation site.
- 免疫原
- Peptide sequence around phosphorylation site of pTyr393, 429 (D-T-Y (p) -T-A) derived from Human ABL1, 2. Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates.
- 亚型
- IgG
- Top Product
- Discover our top product ABL1/ABL2 Primary Antibody
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anti-Abelson Murine Leukemia Viral Oncogene Homolog 1/2 (ABL1/ABL2) (Lys5) antibody
ABL1/ABL2 适用: 人, 小鼠 IHC, WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Abelson Murine Leukemia Viral Oncogene Homolog 1/2 (ABL1/ABL2) (C-Term), (pTyr393), (pTyr439) antibodyABL1/ABL2 适用: 人, 小鼠, 大鼠 IHC, WB, IF, IC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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Western blotting: 1:500-1:1000
Immunohistochemistry: 1:50-1:100
Immunofluorescence: 1:100-1:200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
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- 抗原
- ABL1/2 (ABL1/ABL2) (Abelson Murine Leukemia Viral Oncogene Homolog 1/2 (ABL1/ABL2))
- 别名
- ABL1/2 (ABL1/ABL2 产品)
- 别名
- CABL antibody, ABLL antibody, cb272 antibody, ABL proto-oncogene 2, non-receptor tyrosine kinase antibody, c-abl oncogene 2, non-receptor tyrosine kinase antibody, ABL2 antibody, abl2 antibody
- 背景
- Regulates cytoskeleton remodeling during cell differentiation, cell division and cell adhesion. Localizes to dynamic actin structures, and phosphorylates CRK and CRKL, DOK1, and other proteins controlling cytoskeleton dynamics. Regulates DNA repair potentially by activating the proapoptotic pathway when the DNA damage is too severe to be repaired. Phosphorylates PSMA7 that leads to an inhibition of proteasomal activity and cell cycle transition blocks.
- 分子量
- 210 kDa
- NCBI登录号
- NP_001129, NP_005148
- UniProt
- P42684
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