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GAPDHS 抗体

GAPDHS 适用: Pig WB, IF 宿主: 小鼠 Monoclonal 1D4 unconjugated
产品编号 ABIN361377
发货至: 中国
  • 抗原 See all GAPDHS 抗体
    GAPDHS (Glyceraldehyde-3-Phosphate Dehydrogenase, Spermatogenic (GAPDHS))
    适用
    • 23
    • 18
    • 17
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    Pig
    宿主
    • 30
    • 7
    • 1
    小鼠
    克隆类型
    • 32
    • 6
    单克隆
    标记
    • 16
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This GAPDHS antibody is un-conjugated
    应用范围
    • 30
    • 13
    • 13
    • 7
    • 6
    • 4
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF)
    特异性
    Specific for the ~38k Glyceraldehyde 3-Phosphate Dehydrogenase (GAPDH) protein.
    交叉反应
    人, 小鼠, 大鼠
    预测反应
    Avian, bovine
    纯化方法
    Total IgM fraction--concentrated culture supernatant
    免疫原
    Purified porcine GAPDH
    克隆位点
    1D4
    亚型
    IgM
    Top Product
    Discover our top product GAPDHS Primary Antibody
  • 应用备注
    Recommended Dilution: WB: 1:1,000 IF: 1:100 Quality Control: Western blots performed on each lot.
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    total IgM fraction + 10 mM Sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
  • 抗原
    GAPDHS (Glyceraldehyde-3-Phosphate Dehydrogenase, Spermatogenic (GAPDHS))
    别名
    GAPDHS (GAPDHS 产品)
    背景
    Glyceraldehyde 3-Phosphate Dehydrogenase (GAPDH) is a metabolic enzyme responsible for catalyzing one step in the glycolytic pathway, the reversible oxidative phosphorylation of glyceraldehyde 3-phosphate. Because GAPDH is a protein expressed in large amounts and which is required at all times for important house keeping functions, levels of GAPDH mRNA are often measured and used as standards in studies of mRNA expression. Increasingly, scientists are making use of specific antibodies to GAPDH in comparable studies of levels of protein expression. This antibody can be used as a loading control for western blotting experiments, allowing comparison between the level of this protein and others in a cell or tissue. Apart from a role in glycolysis, GAPDH may have other roles such as in the activation of transcription (1). GAPDH is reported to bind to a variety of other proteins, including the amyloid precursor protein, mutations in which cause some forms of Alzheimer's disease, and the polyglutamine tracts of Huntingtin, the protein product aberrant forms of which are causative of Huntington's disease (2,3). Associations with actin and tubulin have also been reported. The protein may also have a role in the regulation of apoptosis, and interestingly migrates from the cytoplasm into the nucleus when cells become apoptotic (4). Purification: Unpurified, concentrated culture supernatant.
    分子量
    '38 kDa
    基因ID
    26330
    UniProt
    O14556
    途径
    Regulation of Carbohydrate Metabolic Process
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