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TRKA 抗体 (pTyr791)

NTRK1 适用: 人 WB, EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN358249
发货至: 中国
  • 抗原 See all TRKA (NTRK1) 抗体
    TRKA (NTRK1) (Neurotrophic Tyrosine Kinase, Receptor, Type 1 (NTRK1))
    抗原表位
    • 35
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    • 1
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    • 1
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    pTyr791
    适用
    • 238
    • 151
    • 144
    • 15
    • 4
    • 4
    • 1
    • 1
    宿主
    • 247
    • 15
    • 3
    • 2
    克隆类型
    • 239
    • 27
    • 1
    多克隆
    标记
    • 101
    • 18
    • 15
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    • 11
    • 11
    • 11
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    • 6
    • 2
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    • 1
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    This TRKA antibody is un-conjugated
    应用范围
    • 184
    • 99
    • 79
    • 78
    • 51
    • 38
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    • 14
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    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    特异性
    This antibody detects TrKA pTyr791.
    纯化方法
    Protein G Affinity Chromatography. Then, the antibody fraction is peptide affinity purified in a 2-step procedure with control and phosphorylated peptides. The phospho-specific antibody is eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
    免疫原
    This antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding Y791 of human TrkA.
    亚型
    Ig Fraction
    Top Product
    Discover our top product NTRK1 Primary Antibody
  • 应用备注
    ELISA: 1/1,000Western Blot: 1/100-1/500. Dot Blot.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.25 mg/mL
    缓冲液
    PBS with 0.09 % (W/V) Sodium Azide as preservative.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
  • 抗原
    TRKA (NTRK1) (Neurotrophic Tyrosine Kinase, Receptor, Type 1 (NTRK1))
    别名
    TrkA (NTRK1 产品)
    别名
    MTC antibody, TRK antibody, TRK1 antibody, TRKA antibody, Trk-A antibody, p140-TrkA antibody, CDHF12 antibody, CDHR16 antibody, HSCR1 antibody, MEN2A antibody, MEN2B antibody, MTC1 antibody, PTC antibody, RET-ELE1 antibody, RET51 antibody, Trk antibody, C80751 antibody, Tkr antibody, TrkA antibody, trk antibody, trka antibody, CTRKA antibody, trkA antibody, neurotrophic receptor tyrosine kinase 1 antibody, ret proto-oncogene antibody, neurotrophic tyrosine kinase, receptor, type 1 antibody, NTRK1 antibody, RET antibody, Ntrk1 antibody, ntrk1 antibody
    背景
    TrkA is a member of the neurotrophic tyrosine kinase receptor (NTKR) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. The presence of this kinase leads to cell differentiation and may play a role in specifying sensory neuron subtypes. Mutations in the TrkA gene have been associated with congenital insensitivity to pain, anhidrosis, self-mutilating behavior, mental retardation and cancer.Synonyms: High affinity nerve growth factor receptor, NTRK1, Neurotrophic tyrosine kinase receptor type 1, TRK, TRK1-transforming tyrosine kinase protein, Trk-A, p140-TrkA
    分子量
    87511 Da
    基因ID
    4914, 9606
    UniProt
    P04629
    途径
    RTK signaling, Neurotrophin Signaling Pathway, cAMP Metabolic Process
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