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TRPV6 抗体 (AA 320-370)

TRPV6 适用: 兔 WB, IHC 宿主: 绵羊 Polyclonal unconjugated
产品编号 ABIN351306
发货至: 中国
  • 抗原 See all TRPV6 抗体
    TRPV6 (Transient Receptor Potential Cation Channel, Subfamily V, Member 6 (TRPV6))
    抗原表位
    • 16
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 320-370
    适用
    • 26
    • 25
    • 10
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 44
    绵羊
    克隆类型
    • 44
    多克隆
    标记
    • 17
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This TRPV6 antibody is un-conjugated
    应用范围
    • 32
    • 15
    • 14
    • 13
    • 13
    • 6
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    特异性
    Specific for TRPV6.
    免疫原
    A synthetic peptide from aa region 320-370 of rabbit TRPV6 conjugated to an immunogenic carrier protein was used as the antigen.
    亚型
    IgG
    Top Product
    Discover our top product TRPV6 Primary Antibody
  • 应用备注
    A concentration of 10-50 µg/ml is recommended.
    The optimal concentration should be determined by the end user.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
    注意事项
    Avoid freeze and thaw cycles.
    储存条件
    4 °C/-20 °C
    储存方法
    Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
    有效期
    12 months
  • 抗原
    TRPV6 (Transient Receptor Potential Cation Channel, Subfamily V, Member 6 (TRPV6))
    别名
    TRPV6 (TRPV6 产品)
    别名
    ecac antibody, trpv5-6 antibody, TRPV6 antibody, trpv6 antibody, CaT antibody, ECaC antibody, ABP/ZF antibody, CAT1 antibody, CATL antibody, ECAC2 antibody, HSA277909 antibody, LP6728 antibody, ZFAB antibody, CAT antibody, CaT1 antibody, Cac antibody, Ecac2 antibody, Otrpc3 antibody, transient receptor potential cation channel, subfamily V, member 6 antibody, transient receptor potential cation channel subfamily V member 6 antibody, trpv6 antibody, TRPV6 antibody, Trpv6 antibody
    背景
    Function: Calcium selective cation channel probably involved in Ca(2+) uptake in various tissues, including Ca(2+) reabsorption in intestine. The channel is activated by low internal calcium level, probably including intracellular calcium store depletion, and the current exhibits an inward rectification. Inactivation includes both, a rapid Ca(2+)-dependent and a slower Ca(2+)-calmodulin-dependent mechanism, the latter may be regulated by phosphorylation. In vitro, is slowly inhibited by Mg(2+) in a voltage-independent manner. Heteromeric assembly with TRPV5 seems to modify channel properties. TRPV5-TRPV6 heteromultimeric concatemers exhibit voltage-dependent gating.
    Subunit: Homotetramer and probably heterotetramer with TRPV5. Interacts with TRPV5, heterotetramer.
    Subcellular location: Cell membrane, Multi-pass membrane protein.
    Tissue specificity: Expressed in duodenum, proximal jejunum, cecum, and colon. SIMILARITY: Belongs to the transient receptor family, TrpV subfamily. SIMILARITY: Contains 5 ANK repeats. Also known as: Transient receptor potential cation channel subfamily V member 6, TrpV6, Epithelial calcium channel 2, ECaC2, Calcium transport protein 1, CaT1, Trpv6 transient receptor potential cation channel, subfamily V, member 6, CaT1, Ecac2, Otrpc3.
    途径
    TCR Signaling
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