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LST1 抗体

LST1 适用: 人 WB, IP, ICC 宿主: 小鼠 Monoclonal LST1-02 unconjugated
产品编号 ABIN343705
发货至: 中国
  • 抗原 See all LST1 抗体
    LST1 (Leukocyte Specific Transcript 1 (LST1))
    适用
    宿主
    • 30
    • 4
    小鼠
    克隆类型
    • 31
    • 3
    单克隆
    标记
    • 10
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This LST1 antibody is un-conjugated
    应用范围
    • 33
    • 13
    • 13
    • 4
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunoprecipitation (IP), Immunocytochemistry (ICC)
    特异性
    The antibody LST1/02 reacts with an extracellular epitope of LST1, an approximately 6-11 kDa protein expressed as various transmembrane or soluble forms. LST1 is found predominantly on monocytes and dendritic cells. It migrates on SDS PAGE gels as approximately 25-28 kDa molecule.
    交叉反应 (详细)
    Human, Other not determined
    纯化方法
    Purified by protein-A affinity chromatography.
    纯度
    > 95 % (by SDS-PAGE)
    免疫原
    KLH-fused peptide corresponding to amino acids SSEGPDLRGRDKRGT of human LST1
    克隆位点
    LST1-02
    亚型
    IgG1
    Top Product
    Discover our top product LST1 Primary Antibody
  • 应用备注
    Immunoprecipitation: Positive control: RAJI human Burkitt lymphoma cell line.
    Western blotting: The antigen migrates on SDS PAGE gels as approximately 25-28 kDa molecule.
    限制
    仅限研究用
  • 浓度
    1 mg/mL
    缓冲液
    Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Do not freeze.
    储存条件
    4 °C
    储存方法
    Store at 2-8°C. Do not freeze.
  • 抗原
    LST1 (Leukocyte Specific Transcript 1 (LST1))
    别名
    LST1 (LST1 产品)
    别名
    B144 antibody, D6S49E antibody, LST-1 antibody, leukocyte specific transcript 1 antibody, LST1 antibody, Lst1 antibody
    背景
    Leukocyte specific transcript 1,LST1 (leukocyte-specific transcript 1, also known as B144) is expressed in cells of myeloid/erythroid lineage (monocytes, granulocytes, dendritic cells, platelets, erythrocytes). At least 14 alternatively spliced variants (LST1/A –, LST1/N) can be detected, some of them (LST1/A, B, C, G, I, K) are transmembrane cell surface-exposed forms, the other are soluble. LST1 induces production of long, thin filopodia in dendritic cells, has an inhibitory effect on lymphocyte proliferation and may have an immunomodulatory role. LST1/A is an 11 kDa transmembrane adaptor present in membrane rafts and forms spontaneously covalent homodimers. Its intracellular domain contains two tyrosine motifs, one of them being an ITIM very similar to such motifs in Siglec.,LST-1, B144
    基因ID
    7940
    UniProt
    O00453
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