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CD14 抗体

CD14 适用: 小鼠 ELISA 宿主: 小鼠 Monoclonal biG53 unconjugated
产品编号 ABIN343180
发货至: 中国
  • 抗原 See all CD14 抗体
    CD14
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    小鼠
    克隆类型
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    单克隆
    标记
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    This CD14 antibody is un-conjugated
    应用范围
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    ELISA
    特异性
    Membrane bound and soluble mouse CD14. The antibody blocks LPS binding to membrane bound CD14.
    纯化方法
    Protein A affinity column
    免疫原
    Monocytes of mouse
    克隆位点
    BiG53
    亚型
    IgG1
    Top Product
    Discover our top product CD14 Primary Antibody
  • 应用备注
    Suitable for immunostaining of CD14 positive cells and inhibition studies Binds at LPS activated mouse monocytes as well as mouse CD14 transfected cells or recombinant mouse CD14 ELISA. Inhibition of LPS binding to CD14 (Binding at LPS binding site). Up to 1 ug/ml biG53 inhibit binding of FITC-LPS (0.5ug/ml) to 6 x 105 CD14+CHO transfectants (FACS), Binding titre at mouse CD14 transfected CHO-cells: more than 20.000 (ELISA, Flow cytometry)
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Reconstitute with bidistilled water
    浓度
    1 mg/mL
    缓冲液
    PBS, pH 7.16
    储存液
    Without preservative
    储存条件
    -20 °C,-80 °C
  • 抗原
    CD14
    别名
    CD14 (CD14 产品)
    别名
    CD14 molecule antibody, CD14 antigen antibody, CD14 antibody, Cd14 antibody
    背景
    Background: biG 53 represents an excellent marker for CD14. The CD14 glycoprotein, gp 55, is present on most monocytic and macrophages like cell types: monocytes, macrophages, weekly at surface of neutrophiles like Kupffer cells, pleural phagocytic cells and dendritic reticular cells. CD14 is also observed on granulocytes and activated or transformed B-cells. Furthermore CD14 is present in a soluble form in human serum, urine and other body fluids. The CD14 Molecule has been reported to be a receptor for endotoxin. CD14 is anchored to cells by linkage to glycosylphosphatidylinositol (GPI) and functions as a high affinity receptor for LPS-LBP (lipopolysaccharide binding protein)-complexes.
    基因ID
    12475
    NCBI登录号
    NP_033971
    UniProt
    P10810
    途径
    TLR signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades
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